SCHEMBL9762360

SCHEMBL9762360

NCCCCc1nc(N)sc1[N+](=O)[O-]

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
MAPT P10636 2/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
CYP1A2 P05177 1/20 0.32
HRH2 P25021 1/20 0.32
HRH1 P35367 1/20 0.32
HRH4 Q9H3N8 1/20 0.32
GAA P10253 1/20 0.31
SSTR1 P30872 1/20 0.30
SSTR2 P30874 1/20 0.30
SSTR3 P32745 1/20 0.30
SSTR5 P35346 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1101351 0.86 ALDH1A1 (0.39) ALDH1A1MAPTCYP3A4TSHRTDP1
SCHEMBL11325593 0.84 ALDH1A1 (0.41) ALDH1A1MAPTGAA
SCHEMBL11326258 0.84 ALDH1A1 (0.37) ALDH1A1MAPTCYP3A4TSHRTDP1
SCHEMBL9760924 0.79 MAPT (0.31) MAPTSSTR1SSTR2SSTR3SSTR5
SCHEMBL10887538 0.76 MAPT (0.38) ALDH1A1MAPTCYP3A4TSHRTDP1
SCHEMBL9762538 0.74 SMN1; SMN2 (0.38) ALDH1A1MAPTCYP3A4HPGDALOX15
SCHEMBL9761748 0.73 HRH1 (0.32) HRH1
SCHEMBL9762720 0.73 DHFR (0.33) ALDH1A1
SCHEMBL9761308 0.72 NPC1 (0.43) MAPTTDP1CYP1A2GAA
SCHEMBL10400605 0.71 HRH1 (0.33) HRH2HRH1HRH4SSTR1SSTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5026694-A Antitumor agents THE BRITISH COLUMBIA CANCER FOUNDATION (CA) 1991-06-25 US disclosed