Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
| ▸ | GABRE | P78334 | 1/20 | 0.35 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.35 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.35 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.35 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1101351 | 0.95 | ALDH1A1 (0.39) | ALDH1A1MAPTGABRPGABRDGABRA1 | |
| SCHEMBL11325593 | 0.94 | ALDH1A1 (0.41) | ALDH1A1MAPTGAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL9762360 | 0.84 | ALDH1A1 (0.33) | ALDH1A1MAPTGAACYP3A4TSHR | |
| SCHEMBL10887538 | 0.83 | MAPT (0.38) | ALDH1A1MAPTGAASMN1; SMN2MEN1 | |
| SCHEMBL27913052 | 0.77 | ALDH1A1 (0.39) | ALDH1A1MAPTGABRPGABRDGABRA1 | |
| SCHEMBL27912797 | 0.74 | ALDH1A1 (0.33) | ALDH1A1MAPTGABRPGABRDGABRA1 | |
| SCHEMBL27892818 | 0.71 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL27821918 | 0.70 | GABRP (0.50) | ALDH1A1MAPTGABRPGABRDGABRA1 | |
| SCHEMBL958749 | 0.70 | NOS1 (0.46) | ALDH1A1MAPTGAASMN1; SMN2MEN1 | |
| SCHEMBL9457581 | 0.69 | KCNH2 (0.45) | ALDH1A1MAPTGAASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108689961-A | 2-(5- nitrothiazole -2- bases)Imino group -4- thiazolinone derivatives and the preparation method and application thereof | 中国医学科学院药物研究所 | 2018-10-23 | — | — | CN | disclosed |
| US-4252530-A | USING A BASE AS DISCHARGE AGENT IN A DISCHARGE RESIST PASTE AND HEATING | CASSELLA AKTIENGESELLSCHAFT (DE) | 1981-02-24 | — | — | US | disclosed |