Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22375160 | 0.75 | GAA (0.46) | GAAALDH1A1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL9761816 | 0.74 | GAA (0.45) | GAAALDH1A1SMN1; SMN2MAPTADORA3 | |
| SCHEMBL9761852 | 0.64 | L3MBTL1 (0.41) | GAAALDH1A1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL9762636 | 0.63 | RIPK1 (0.41) | GAAALDH1A1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL9762478 | 0.63 | KMT2A (0.32) | ALDH1A1RAB9AKMT2A | |
| SCHEMBL9761080 | 0.62 | MAT2A (0.34) | ALDH1A1RAB9AMAPTALOX15HTT | |
| SCHEMBL9761859 | 0.62 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL9762410 | 0.61 | ALOX15 (0.42) | GAAALDH1A1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL9762423 | 0.61 | ALDH1A1 (0.35) | GAAALDH1A1RAB9AMAPTMAPK1 | |
| SCHEMBL9762365 | 0.61 | ALDH1A1 (0.45) | GAAALDH1A1SMN1; SMN2RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |