Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 4/20 | 0.44 |
| ▸ | ACHE | P22303 | 4/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | P4HB | P07237 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763666 | 0.86 | MAOA (0.46) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL9762652 | 0.84 | POLB (0.51) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| Benzene SCHEMBL27952372 | 0.77 | MAOA (0.65) | CNR1CNR2KDM4ELMNAP4HB | |
| SCHEMBL9320936 | 0.76 | MAOA (0.62) | CNR1CNR2KDM4ELMNAP4HB | |
| SCHEMBL23060737 | 0.74 | CETP (0.63) | HDAC3HDAC1HDAC2HDAC8POLB | |
| SCHEMBL9763241 | 0.74 | S1PR1 (0.56) | CNR1CNR2KDM4ELMNABCHE | |
| SCHEMBL14637774 | 0.73 | CETP (0.58) | HDAC3HDAC1HDAC2HDAC8POLB | |
| SCHEMBL9764394 | 0.73 | SIGMAR1 (0.69) | BCHE | |
| SCHEMBL10477755 | 0.73 | SIGMAR1 (0.69) | BCHE | |
| SCHEMBL10952736 | 0.73 | MAOA (0.77) | HDAC3HDAC1HDAC2HDAC8NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990505-A | Treating asthma, bronchitis; adrenergic stimulants | GLAXO GROUP LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |