Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764536 | 0.86 | SCN8A (0.57) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL9763358 | 0.86 | SIGMAR1 (0.51) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL9762649 | 0.84 | HDAC3 (0.48) | POLBHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL9762664 | 0.84 | SIGMAR1 (0.49) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL9763305 | 0.83 | BCHE (0.46) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL9762667 | 0.83 | SLC2A1 (0.50) | POLBTDP1HDAC1TRPV1NPC1 | |
| SCHEMBL5040279 | 0.79 | EPHX2 (0.65) | HDAC3HDAC1HDAC2HDAC8ALDH1A1 | |
| SCHEMBL9762923 | 0.79 | AR (0.52) | S1PR1S1PR3S1PR2ALDH1A1CNR2 | |
| SCHEMBL10477755 | 0.79 | SIGMAR1 (0.69) | TDP1MAPTGAA | |
| SCHEMBL9764394 | 0.79 | SIGMAR1 (0.69) | TDP1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990505-A | Treating asthma, bronchitis; adrenergic stimulants | GLAXO GROUP LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |