Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.49 |
| ▸ | BCHE | P06276 | 5/20 | 0.48 |
| ▸ | ACHE | P22303 | 3/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.44 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763358 | 0.91 | SIGMAR1 (0.51) | SIGMAR1BCHEACHEMAOACHRM2 | |
| SCHEMBL9764536 | 0.88 | SCN8A (0.57) | SIGMAR1BCHEACHEMAOACHRM2 | |
| SCHEMBL9762667 | 0.87 | SLC2A1 (0.50) | SIGMAR1BCHEACHEMAOAHDAC1 | |
| SCHEMBL9763305 | 0.85 | BCHE (0.46) | SIGMAR1BCHEACHEMAOACHRM2 | |
| SCHEMBL9762652 | 0.84 | POLB (0.51) | HDAC3HDAC1HDAC2HDAC8NCOR2 | |
| SCHEMBL10477755 | 0.83 | SIGMAR1 (0.69) | SIGMAR1BCHEMAOACHRM2 | |
| SCHEMBL9764394 | 0.83 | SIGMAR1 (0.69) | SIGMAR1BCHEMAOACHRM2 | |
| Hydrochloric Acid SCHEMBL9258435 | 0.82 | SIGMAR1 (0.67) | SIGMAR1BCHEMAOACHRM2 | |
| SCHEMBL9763689 | 0.82 | SIGMAR1 (0.52) | SIGMAR1BCHEACHEMAOACHRM2 | |
| SCHEMBL27716955 | 0.81 | SIGMAR1 (0.58) | SIGMAR1BCHEACHEMAOACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990505-A | Treating asthma, bronchitis; adrenergic stimulants | GLAXO GROUP LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |