Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 3/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763358 | 0.90 | SIGMAR1 (0.51) | SIGMAR1BCHEACHEHDAC1MEN1 | |
| SCHEMBL9764536 | 0.87 | SCN8A (0.57) | SIGMAR1BCHEACHEHDAC1MEN1 | |
| SCHEMBL9762664 | 0.87 | SIGMAR1 (0.49) | SIGMAR1BCHEACHEHDAC1KDM4E | |
| SCHEMBL9763305 | 0.84 | BCHE (0.46) | SLC2A1SIGMAR1BCHEACHEHDAC1 | |
| SCHEMBL9762652 | 0.83 | POLB (0.51) | HDAC1POLBTDP1SMN1; SMN2TRPV1 | |
| SCHEMBL10477755 | 0.83 | SIGMAR1 (0.69) | SIGMAR1BCHEMEN1KMT2ATDP1 | |
| SCHEMBL9764394 | 0.83 | SIGMAR1 (0.69) | SIGMAR1BCHEMEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL9258435 | 0.81 | SIGMAR1 (0.67) | SIGMAR1BCHEMEN1KMT2ATDP1 | |
| SCHEMBL9763689 | 0.81 | SIGMAR1 (0.52) | SIGMAR1BCHEACHEHDAC1MAOA | |
| SCHEMBL27716955 | 0.80 | SIGMAR1 (0.58) | SIGMAR1BCHEACHEMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990505-A | Treating asthma, bronchitis; adrenergic stimulants | GLAXO GROUP LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |