Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9761689 | 0.73 | KCNH2 (0.36) | ALDH1A1MAPT | |
| SCHEMBL3636660 | 0.69 | MAPT (0.33) | ALDH1A1MAPTHPGDHTTATM | |
| SCHEMBL9762596 | 0.67 | MAPT (0.31) | MAPT | |
| SCHEMBL9762325 | 0.66 | ALDH1A1 (0.33) | ALDH1A1MAPTKMT2AHPGDMEN1 | |
| SCHEMBL9761859 | 0.65 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL9762423 | 0.64 | ALDH1A1 (0.35) | ALDH1A1MAPTL3MBTL1HTTTP53 | |
| SCHEMBL9762365 | 0.64 | ALDH1A1 (0.45) | ALDH1A1MAPTKMT2AMEN1POLB | |
| SCHEMBL9762344 | 0.61 | ALDH1A1 (0.38) | ALDH1A1MAPTKMT2AHPGDMEN1 | |
| SCHEMBL9762284 | 0.61 | ALDH1A1 (0.35) | ALDH1A1MAPTL3MBTL1HTTSMN1; SMN2 | |
| SCHEMBL3632711 | 0.61 | MAPT (0.32) | MAPTKMT2AMEN1L3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |