Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.31 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9762264 | 0.72 | KCNH2 (0.37) | ALDH1A1HTTMAPTMAPK1 | |
| SCHEMBL9761080 | 0.70 | MAT2A (0.34) | ALDH1A1RAB9AHTTALOX15MAPT | |
| SCHEMBL28286529 | 0.70 | MAPT (0.37) | ALDH1A1GAARAB9AMAPT | |
| SCHEMBL6638188 | 0.67 | GALR3 (0.33) | MAPT | |
| SCHEMBL11220123 | 0.67 | TDP1 (0.37) | ALDH1A1GAATDP1RAB9AHTT | |
| SCHEMBL9761367 | 0.66 | ALOX15 (0.38) | ALDH1A1GAATDP1ALOX15MAPT | |
| SCHEMBL9124018 | 0.66 | TDP1 (0.38) | ALDH1A1GAATDP1RAB9AHTT | |
| SCHEMBL9762665 | 0.64 | ALDH1A1 (0.41) | ALDH1A1GAATDP1RAB9AHTT | |
| SCHEMBL11499585 | 0.64 | TDP1 (0.50) | ALDH1A1GAATDP1RAB9AHTT | |
| SCHEMBL9762478 | 0.64 | KMT2A (0.32) | ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |