SCHEMBL976275

SCHEMBL976275

CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC(OC(=O)CCO)[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 8/20 0.56
ALDH1A1 P00352 7/20 0.56
LMNA P02545 6/20 0.56
MAPT P10636 5/20 0.56
SMN1; SMN2 Q16637 5/20 0.56
CYP2C9 P11712 3/20 0.56
TSHR P16473 3/20 0.56
MAPK1 P28482 3/20 0.56
NR1I2 O75469 3/20 0.56
SERPINA6 P08185 3/20 0.56
HIF1A Q16665 2/20 0.56
CYP2C19 P33261 2/20 0.56
ABCB11 O95342 2/20 0.56
NR3C1 P04150 2/20 0.56
SHBG P04278 2/20 0.56
PGR P06401 2/20 0.56
AR P10275 2/20 0.56
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
KDM4E B2RXH2 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28255051 0.95 CYP3A4 (0.59) CYP3A4ALDH1A1LMNAMAPTSMN1; SMN2
SCHEMBL2561836 0.93 CYP3A4 (0.56) CYP3A4ALDH1A1LMNAMAPTSMN1; SMN2
SCHEMBL2042111 0.93 CYP3A4 (0.58) CYP3A4ALDH1A1LMNAMAPTSMN1; SMN2
SCHEMBL11023737 0.91 CYP3A4 (0.60) CYP3A4ALDH1A1LMNAMAPTSMN1; SMN2
SCHEMBL28137569 0.90 CYP3A4 (0.54) CYP3A4ALDH1A1LMNAMAPTSMN1; SMN2
SCHEMBL571724 0.90 LMNA (0.62) CYP3A4ALDH1A1LMNAMAPTSMN1; SMN2
SCHEMBL5331 0.90 LMNA (0.62) CYP3A4ALDH1A1LMNAMAPTSMN1; SMN2
SCHEMBL571134 0.90 CYP19A1 (0.61) CYP3A4ALDH1A1LMNAMAPTSMN1; SMN2
SCHEMBL5425553 0.90 LMNA (0.64) CYP3A4ALDH1A1LMNAMAPTSMN1; SMN2
SCHEMBL353517 0.90 LMNA (0.64) CYP3A4ALDH1A1LMNAMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1862167-A2 Methods and formulations for the treatment of female sexual dysfunction Barr Laboratories, Inc. (US) 2007-12-05 EP claimed
EP-1848541-A2 METHOD AND DEVICE FOR OPHTHALMIC ADMINISTRATION OF ACTIVE PHARMACEUTICAL INGREDIENTS Pharmalight Inc. (US) 2007-10-31 EP claimed
EP-1359920-B1 USES OF ORAL FORMULATIONS FOR THE TREATMENT OF FEMALE SEXUAL DYSFUNCTION BARR LAB INC (US) 2007-08-22 EP claimed
WO-2006082588-A2 METHOD AND DEVICE FOR OPHTHALMIC ADMINISTRATION OF ACTIVE PHARMACEUTICAL INGREDIENTS PHARMALIGHT INC. (US) 2006-08-10 WO claimed
US-20050042268-A1 Pharmaceutical composition and method for transdermal drug delivery PERRIGO ISRAEL PHARMACEUTICALS LTD. (IL) 2005-02-24 US claimed
US-20050025833-A1 Pharmaceutical composition and method for transdermal drug delivery PERRIGO ISRAEL PHARMACEUTICALS LTD. (IL) 2005-02-03 US claimed
US-20050020552-A1 Pharmaceutical composition and method for transdermal drug delivery PERRIGO ISRAEL PHARMACEUTICALS LTD. (IL) 2005-01-27 US claimed
US-20040259817-A1 Methods and formulations for the treatment of female sexual dysfunction BARR LABORATORIES, INC. 2004-12-23 US claimed
EP-1359920-A2 METHODS AND FORMULATIONS FOR THE TREATMENT OF FEMALE SEXUAL DYSFUNCTION Endeavor Pharmaceuticals (US) 2003-11-12 EP claimed
US-20020107230-A1 Methods and formulations for the treatment of female sexual dysfunction BARR LABORATORIES, INC. 2002-08-08 US claimed
WO-2002051420-A2 METHODS AND FORMULATIONS FOR THE TREATMENT OF FEMALE SEXUAL DYSFUNCTION ENDEAVOR PHARMACEUTICALS (US) 2002-07-04 WO claimed
US-20190091149-A1 Oil foamable carriers and formulations FOAMIX PHARMACEUTICALS LTD. 2019-03-28 US disclosed
EP-2826371-B1 Methods and compositions for inhibiting integrins using tellurium-containing compounds FERAMDA LTD (IL) 2019-01-02 EP disclosed
US-20180133149-A1 DRUG-DELIVERING COMPOSITE STRUCTURES ZILBERMAN, MEITAL (IL) 2018-05-17 US disclosed
US-20170348418-A1 Foamable Vehicle and Pharmaceutical Compositions Thereof FOAMIX PHARMACEUTICALS, LTD. (IL) 2017-12-07 US disclosed
US-20050020552-A1 Pharmaceutical composition and method for transdermal drug delivery PERRIGO ISRAEL PHARMACEUTICALS LTD. (IL) 2005-01-27 US disclosed
US-20040259817-A1 Methods and formulations for the treatment of female sexual dysfunction BARR LABORATORIES, INC. 2004-12-23 US disclosed
EP-1359920-A2 METHODS AND FORMULATIONS FOR THE TREATMENT OF FEMALE SEXUAL DYSFUNCTION Endeavor Pharmaceuticals (US) 2003-11-12 EP disclosed
US-20020107230-A1 Methods and formulations for the treatment of female sexual dysfunction BARR LABORATORIES, INC. 2002-08-08 US disclosed
WO-2002051420-A2 METHODS AND FORMULATIONS FOR THE TREATMENT OF FEMALE SEXUAL DYSFUNCTION ENDEAVOR PHARMACEUTICALS (US) 2002-07-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190091149-A1 Oil foamable carriers and formulations LIPA, PTGER1, TTPA CYP3A4 3480/4885ALDH1A1 3782/4885LMNA 500/4885
US-20180133149-A1 DRUG-DELIVERING COMPOSITE STRUCTURES PLOD3, NEFM, APMAP CYP3A4 2006/4885ALDH1A1 1424/4885LMNA 383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.