SCHEMBL9762780

SCHEMBL9762780

Oc1ccc(Oc2ccc(Br)cc2F)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
ESR1 P03372 1/20 0.45
ESR2 Q92731 1/20 0.45
TAAR5 O14804 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
ALOX15 P16050 1/20 0.41
HSPB1 P04792 1/20 0.41
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40
HPGD P15428 1/20 0.40
HTT P42858 1/20 0.40
ATM Q13315 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
LTA4H P09960 1/20 0.39
NR1H2 P55055 1/20 0.39
BAX Q07812 1/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29084784 0.89 ALOX15 (0.41) MEN1KMT2AESR1ESR2TAAR5
SCHEMBL10561428 0.82 MAPT (0.57) MEN1KMT2AALOX15HSPB1MAPT
SCHEMBL5545867 0.82 HSPB1 (0.41) HSPB1LMNAMAPTHTTALDH1A1
SCHEMBL9342871 0.81 HSPB1 (0.58) MEN1KMT2AESR1ESR2TAAR5
SCHEMBL1129244 0.81 SLC6A4 (0.50) HSPB1LTA4HALDH1A1MAPK1TDP1
SCHEMBL27266032 0.80 MAPK1 (0.58) MEN1KMT2AALOX15LMNAMAPT
SCHEMBL9762032 0.79 MAPT (0.53) KMT2ALMNAMAPTHPGDHTT
SCHEMBL8683893 0.79 STK39 (0.46) MEN1KMT2AESR1ESR2ALOX15
SCHEMBL10559362 0.79 SCN9A (0.50) MEN1KMT2AESR1ESR2MAPT
SCHEMBL30760842 0.79 MET (0.41) MEN1KMT2AHSPB1LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4751329-A HERBICIDE INTERMEDIATES THE DOW CHEMICAL COMPANY (US) 1988-06-14 US claimed
EP-0024852-B1 2,3-DIHYDRO-1H-INDOLE DERIVATIVES AND INTERMEDIATES THEREFOR, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE DERIVATIVES AND THEIR PREPARATION AMERICAN HOME PRODUCTS CORPORATION (US) 1986-09-03 EP claimed
JP-1279856-A None JP disclosed
US-5012017-A Peroxide oxidation of halogenated phenoxyphenones to phenoxyophenyl esters, then conversions to phenoxyphenols DOWELANCO (US) 1991-04-30 US disclosed
WO-1990009979-A1 METHODS FOR THE PREPARATION OF BROMINATED INTERMEDIATES THE DOW CHEMICAL COMPANY (US) 1990-09-07 WO disclosed
CN-1045094-A The method for preparing the bromination intermediate DOW CHEMICAL CO (US) 1990-09-05 CN disclosed
EP-0384043-A2 Methods for the preparation of brominated intermediates THE DOW CHEMICAL COMPANY (US) 1990-08-29 EP disclosed
JP-H01279856-A FLUOROPHENOXYPHENOLS DOW CHEM CO:THE 1989-11-10 JP disclosed
CN-1034917-A The preparation method of (phenoxy group phenoxy group) propionic acid ester DOW CHEMICAL CO (US) 1989-08-23 CN disclosed
WO-1989006227-A1 PHENOXYPHENOXYPROPIONATES, INTERMEDIATES THEREOF AND METHODS OF PREPARATION THE DOW CHEMICAL COMPANY (US) 1989-07-13 WO disclosed
EP-0322983-A1 Phenoxyphenoxypropionates, intermediates thereof and methods of preparation THE DOW CHEMICAL COMPANY (US) 1989-07-05 EP disclosed
US-4808750-A (PRE-OR POST-)EMERGENCE HERBICIDE FOR BROAD LEAF PLANTS THE DOW CHEMICAL COMPANY (US) 1989-02-28 US disclosed
US-4757155-A Process for the preparation of optically active 2-[4-(2',4'-dihalophenoxy)phenoxy]propionic acids THE DOW CHEMICAL COMPANY (US) 1988-07-12 US disclosed
US-4751329-A HERBICIDE INTERMEDIATES THE DOW CHEMICAL COMPANY (US) 1988-06-14 US disclosed
EP-0138359-B1 HERBICIDAL FLUOROPHENOXYPHENOXYPROPIONATES, DERIVATIVES THEREOF AND RELATED COMPOUNDS THE DOW CHEMICAL COMPANY (US) 1988-05-11 EP disclosed
US-4725683-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1988-02-16 US disclosed
US-4642338-A HERBICIDES THE DOW CHEMICAL COMPANY (US) 1987-02-10 US disclosed
US-4550192-A PRE-AND POSTEMERGENCE HERBICIDES THE DOW CHEMICAL COMPANY (US) 1985-10-29 US disclosed
EP-0138359-A2 Herbicidal Fluorophenoxyphenoxypropionates, derivatives thereof and related compounds THE DOW CHEMICAL COMPANY (US) 1985-04-24 EP disclosed