Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 4/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL536918 | 0.84 | TSHR (0.43) | ALDH1A1TRPA1 | |
| SCHEMBL9423581 | 0.78 | CYP11B2 (0.52) | CYP11B2CYP19A1CYP11B1ALDH1A1MAPT | |
| SCHEMBL28821314 | 0.77 | TDP1 (0.44) | ALDH1A1NPC1RAB9ACYP1A2SMN1; SMN2 | |
| SCHEMBL28821371 | 0.77 | NFE2L2 (0.47) | CYP11B2CYP11B1NPC1RAB9ACYP1A2 | |
| SCHEMBL5545232 | 0.74 | PPARG (0.47) | MAPTNPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL9278742 | 0.74 | LTA4H (0.52) | CYP19A1ALDH1A1MAPTSLC6A2SLC6A3 | |
| SCHEMBL8695868 | 0.74 | PPARG (0.47) | MAPTCYP1A2HPGDCYP1B1TRPA1 | |
| SCHEMBL5546634 | 0.74 | TRPA1 (0.63) | ALDH1A1MAPTCYP1A2KDM4ECYP3A4 | |
| SCHEMBL4179961 | 0.74 | NFE2L2 (0.52) | ALDH1A1MAPTCYP1A2CYP2D6HPGD | |
| SCHEMBL28821435 | 0.74 | CYP11B1 (0.42) | CYP11B2CYP19A1CYP11B1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5070097-A | MITICIDES | ICI AMERICAS INC. (US) | 1991-12-03 | — | — | US | disclosed |
| US-5064846-A | Heterocyclic insecticides | ICI AMERICAS INC. (US) | 1991-11-12 | — | — | US | disclosed |
| US-4994473-A | For plants | ICI AMERICAS INC. (US) | 1991-02-19 | — | — | US | disclosed |
| US-4992453-A | Certain thioimidate and amidine insecticides | ICI AMERICAS INC. (US) | 1991-02-12 | — | — | US | disclosed |
| US-4931448-A | Thiomidate insecticides | ICI AMERICAS INC. (US) | 1990-06-05 | — | — | US | disclosed |
| EP-0317266-A2 | Novel thioimidate and amidine insecticides | ICI AMERICAS INC. (US) | 1989-05-24 | — | — | EP | disclosed |
| EP-0317259-A2 | Heterocyclic insecticides | ICI AMERICAS INC. (US) | 1989-05-24 | — | — | EP | disclosed |