SCHEMBL15566288

SCHEMBL15566288

O=P(c1ccccc1)(c1ccccc1)c1ccc2ccccc2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.47
CYP3A4 P08684 2/20 0.47
HSD17B10 Q99714 2/20 0.47
HPGD P15428 1/20 0.47
LMNA P02545 3/20 0.46
RAB9A P51151 5/20 0.44
NPC1 O15118 4/20 0.44
MAPT P10636 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
CYP1A2 P05177 2/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
HIF1A Q16665 1/20 0.42
CA2 P00918 2/20 0.41
GPR84 Q9NQS5 1/20 0.41
CA1 P00915 1/20 0.41
PTPN1 P18031 1/20 0.40
MEN1 O00255 5/20 0.40
KMT2A Q03164 5/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14339277 1.00 ALDH1A1 (0.47) ALDH1A1CYP3A4HSD17B10HPGDLMNA
SCHEMBL31212637 1.00 ALDH1A1 (0.47) ALDH1A1CYP3A4HSD17B10HPGDLMNA
SCHEMBL21503905 1.00 ALDH1A1 (0.47) ALDH1A1CYP3A4HSD17B10HPGDLMNA
SCHEMBL14339280 1.00 ALDH1A1 (0.47) ALDH1A1CYP3A4HSD17B10HPGDLMNA
SCHEMBL30544386 1.00 ALDH1A1 (0.47) ALDH1A1CYP3A4HSD17B10HPGDLMNA
SCHEMBL14339279 1.00 ALDH1A1 (0.47) ALDH1A1CYP3A4HSD17B10HPGDLMNA
SCHEMBL14339265 0.96 ALDH1A1 (0.44) ALDH1A1CYP3A4HSD17B10HPGDLMNA
SCHEMBL14339270 0.96 ALDH1A1 (0.44) ALDH1A1CYP3A4HSD17B10HPGDLMNA
SCHEMBL14339274 0.96 GPR84 (0.44) ALDH1A1CYP3A4HSD17B10HPGDLMNA
SCHEMBL16815192 0.96 LMNA (0.48) ALDH1A1CYP3A4HSD17B10HPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2880041-B1 PROCESS FOR PREPARATION OF ARYL PHOSPHOROUS COMPOUNDS COUNCIL SCIENT IND RES (IN) 2018-10-10 EP claimed
US-20230399329-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR FORMING ORGANIC LAYER LT MATERIALS CO., LTD. (KR) 2023-12-14 US disclosed
US-20230399329-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR FORMING ORGANIC LAYER LT MATERIALS CO., LTD. (KR) 2023-12-14 US disclosed
US-20230397496-A1 DOUBLE-CAPPED MICROMOLECULE ELECTRON DONOR MATERIAL AND PREPARATION AND APPLICATION THEREOF CHONGQING INSTITUTE OF GREEN AND INTELLIGENT TECHNOLOGY, CHINESE ACADEMY OF SCIENCES (CN) 2023-12-07 US disclosed
CN-112574251-B Preparation method of visible light-promoted 1-phosphonyl-2-naphthol derivative 河南工业大学 2022-09-30 CN disclosed
CN-109524549-B Double-functional-layer full-small-molecule non-fullerene-system organic solar cell 中国科学院重庆绿色智能技术研究院 2022-08-16 CN disclosed
CN-114891023-A Double-end-capped small-molecule electron donor material and preparation and application thereof 中国科学院重庆绿色智能技术研究院 2022-08-12 CN disclosed
CN-114874205-A Electron-deficient heterocyclic core small-molecule electron donor material and preparation and application thereof 中国科学院重庆绿色智能技术研究院 2022-08-09 CN disclosed
CN-114437316-A Terpolymer donor material and preparation and application thereof 中国科学院重庆绿色智能技术研究院 2022-05-06 CN disclosed
CN-114262426-A Pi-bridge fluorine substituted selenizing polymer receptor material and preparation and application thereof 中国科学院重庆绿色智能技术研究院 2022-04-01 CN disclosed
CN-109524549-A The non-fullerene system organic solar batteries of the full small molecule of bifunctional layer 中国科学院重庆绿色智能技术研究院 2019-03-26 CN disclosed
EP-2880041-B1 PROCESS FOR PREPARATION OF ARYL PHOSPHOROUS COMPOUNDS COUNCIL SCIENT IND RES (IN) 2018-10-10 EP disclosed
US-9200018-B2 Process for preparation of aryl phosphorous compounds COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2015-12-01 US disclosed
US-9200018-B2 Process for preparation of aryl phosphorous compounds COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2015-12-01 US disclosed
US-9200018-B2 Process for preparation of aryl phosphorous compounds COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2015-12-01 US disclosed
US-20150210725-A1 PROCESS FOR PREPARATION OF ARYL PHOSPHOROUS COMPOUNDS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2015-07-30 US disclosed
US-20150210725-A1 PROCESS FOR PREPARATION OF ARYL PHOSPHOROUS COMPOUNDS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2015-07-30 US disclosed
US-20150210725-A1 PROCESS FOR PREPARATION OF ARYL PHOSPHOROUS COMPOUNDS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2015-07-30 US disclosed
EP-2880041-A1 PROCESS FOR PREPARATION OF ARYL PHOSPHOROUS COMPOUNDS Council of Scientific & Industrial Research (IN) 2015-06-10 EP disclosed
WO-2014024212-A1 PROCESS FOR PREPARATION OF ARYL PHOSPHOROUS COMPOUNDS COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2014-02-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150210725-A1 PROCESS FOR PREPARATION OF ARYL PHOSPHOROUS COMPOUNDS PFAS, PAICS, INPP5B ALDH1A1 1195/4885CYP3A4 804/4885HSD17B10 4070/4885
US-20230397496-A1 DOUBLE-CAPPED MICROMOLECULE ELECTRON DONOR MATERIAL AND PREPARATION AND APPLICATION THEREOF STOML2, NME4, STOM ALDH1A1 2225/4885CYP3A4 4226/4885HSD17B10 4513/4885
US-20230399329-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME, AND COMPOSITION FOR FORMING ORGANIC LAYER CRY1, ORC3, ODC1 ALDH1A1 45/4885CYP3A4 29/4885HSD17B10 1334/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.