Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.38 |
| ▸ | CES1 | P23141 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9762903 | 0.89 | FAAH (0.42) | FAAHCES1MAOB | |
| SCHEMBL9763406 | 0.86 | FAAH (0.46) | FAAHCES1MAOB | |
| SCHEMBL9763654 | 0.84 | FAAH (0.39) | FAAHCES1HRH4HRH3 | |
| SCHEMBL9763575 | 0.81 | SPHK1 (0.43) | FAAHCES1 | |
| SCHEMBL9762547 | 0.80 | KCNH2 (0.53) | FAAHCES1HRH4HRH3 | |
| SCHEMBL6956921 | 0.79 | GRIN2D (0.45) | CES1MAOAMAOB | |
| SCHEMBL9763073 | 0.79 | FAAH (0.39) | FAAHCES1EGFRERBB2 | |
| SCHEMBL9763598 | 0.78 | FFAR4 (0.43) | HRH4HRH3 | |
| SCHEMBL9763665 | 0.78 | SNCA (0.44) | — | |
| SCHEMBL6961364 | 0.77 | MAOA (0.54) | FAAHCES1MAOAMAOBOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990505-A | Treating asthma, bronchitis; adrenergic stimulants | GLAXO GROUP LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |