Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.46 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | MC5R | P33032 | 1/20 | 0.38 |
| ▸ | MC3R | P41968 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9762903 | 0.97 | FAAH (0.42) | FAAHCES1MAOBLPAR1LPAR5 | |
| SCHEMBL9762900 | 0.86 | FAAH (0.38) | FAAHCES1MAOB | |
| SCHEMBL9763654 | 0.85 | FAAH (0.39) | FAAHCES1LPAR1LPAR5MC4R | |
| SCHEMBL6956260 | 0.84 | RCE1 (0.49) | FAAHCES1MAOBLPAR1LPAR5 | |
| SCHEMBL6967760 | 0.84 | RCE1 (0.49) | FAAHCES1MAOBLPAR1LPAR5 | |
| SCHEMBL9763575 | 0.83 | SPHK1 (0.43) | FAAHCES1 | |
| SCHEMBL9762547 | 0.82 | KCNH2 (0.53) | FAAHCES1SIGMAR1MC4R | |
| SCHEMBL9763263 | 0.82 | L3MBTL1 (0.45) | FAAHCES1 | |
| SCHEMBL9763073 | 0.81 | FAAH (0.39) | FAAHCES1LPAR1LPAR5 | |
| SCHEMBL9763598 | 0.81 | FFAR4 (0.43) | NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990505-A | Treating asthma, bronchitis; adrenergic stimulants | GLAXO GROUP LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |