Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | HTR5A | P47898 | 3/20 | 0.37 |
| ▸ | REN | P00797 | 2/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763575 | 0.86 | SPHK1 (0.43) | FAAHCES1HTR5ASPHK1 | |
| SCHEMBL9762903 | 0.85 | FAAH (0.42) | FAAHCES1LPAR1LPAR5 | |
| SCHEMBL9763406 | 0.81 | FAAH (0.46) | FAAHCES1LPAR1LPAR5 | |
| SCHEMBL9762547 | 0.81 | KCNH2 (0.53) | FAAHCES1 | |
| SCHEMBL9763598 | 0.80 | FFAR4 (0.43) | — | |
| SCHEMBL9762900 | 0.79 | FAAH (0.38) | FAAHCES1EGFRERBB2 | |
| SCHEMBL9764529 | 0.78 | L3MBTL1 (0.45) | — | |
| SCHEMBL9763654 | 0.78 | FAAH (0.39) | FAAHCES1LPAR1LPAR5 | |
| SCHEMBL9763665 | 0.75 | SNCA (0.44) | — | |
| SCHEMBL9763263 | 0.75 | L3MBTL1 (0.45) | FAAHCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990505-A | Treating asthma, bronchitis; adrenergic stimulants | GLAXO GROUP LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |