SCHEMBL8654136

SCHEMBL8654136

CCCc1cc(C(=O)c2ccc(O)c(CCC)c2)ccc1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.50
HSP90AB1 P08238 1/20 0.50
PKM P14618 1/20 0.50
ALOX5 P09917 1/20 0.47
POLB P06746 1/20 0.47
PRKCI P41743 1/20 0.47
SLC22A6 Q4U2R8 1/20 0.47
SLC22A8 Q8TCC7 1/20 0.47
HSD17B1 P14061 1/20 0.46
HTT P42858 2/20 0.45
ALDH1A1 P00352 2/20 0.45
HPGD P15428 2/20 0.45
CNR2 P34972 1/20 0.44
CA2 P00918 3/20 0.44
PTPN1 P18031 1/20 0.43
PTPN11 Q06124 1/20 0.43
SIRT1 Q96EB6 1/20 0.43
HIF1A Q16665 2/20 0.43
TP53 P04637 1/20 0.43
CYP1A2 P05177 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6933360 0.92 PPARG (0.52) HSP90AA1HSP90AB1ALDH1A1HPGDCNR2
SCHEMBL24648555 0.90 LMNA (0.52) HSP90AA1HSP90AB1PKMALOX5POLB
SCHEMBL13114560 0.87 ALDH1A1 (0.53) POLBSLC22A6SLC22A8ALDH1A1HPGD
SCHEMBL24648579 0.87 F10 (0.48) ALOX5HSD17B1ALDH1A1HPGDCNR2
SCHEMBL9616832 0.87 PKM (0.68) HSP90AA1HSP90AB1PKMALOX5POLB
SCHEMBL2003391 0.87 POLB (0.53) HSP90AA1HSP90AB1PKMALOX5POLB
SCHEMBL9763047 0.86 HSP90AA1 (0.65) HSP90AA1HSP90AB1PKMPOLBSLC22A6
SCHEMBL2005197 0.85 HSP90AA1 (0.47) HSP90AA1HSP90AB1PKMALOX5POLB
SCHEMBL1024088 0.85 HTT (0.62) HSP90AA1HSP90AB1PKMALOX5POLB
SCHEMBL481263 0.84 HSP90AA1 (0.50) HSP90AA1HSP90AB1PKMALOX5POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0566423-B1 Electrophotographic photoconductor MITSUBISHI CHEM CORP (JP) 1998-10-21 EP disclosed
US-5378567-A 4-4*-dihydroxybenzophenone and p,p*-dihydroxydiphenylmethane derivatives as monomers; durability; wear resistance MITSUBISHI KASEI CORPORATION (JP) 1995-01-03 US disclosed
EP-0566423-A1 Electrophotographic photoconductor Mitsubishi Chemical Corporation (JP) 1993-10-20 EP disclosed