Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8340727 | 0.87 | PKM (0.66) | PKMHSP90AA1HSP90AB1HKDC1HTT | |
| SCHEMBL9763047 | 0.80 | HSP90AA1 (0.65) | PKMSLC22A6SLC22A8HSP90AA1HSP90AB1 | |
| SCHEMBL11674343 | 0.76 | EGFR (0.60) | PKMHSP90AA1HKDC1ALDH1A1HPGD | |
| SCHEMBL12808995 | 0.76 | SYK (0.58) | HSP90AA1HKDC1CA2CA1ALDH1A1 | |
| SCHEMBL8654136 | 0.76 | HSP90AA1 (0.50) | PKMSLC22A6SLC22A8HSP90AA1HSP90AB1 | |
| SCHEMBL13030044 | 0.75 | AMY1A (0.60) | PKMHTTPOLBMAOBALDH1A1 | |
| SCHEMBL10069990 | 0.75 | CA1 (0.52) | CA2POLBCA1SLC6A2SLC6A4 | |
| SCHEMBL27759343 | 0.75 | MAPT (0.46) | CA2CA1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL27405963 | 0.75 | PKM (0.48) | PKMSLC22A6SLC22A8HSP90AA1HSP90AB1 | |
| SCHEMBL27927657 | 0.74 | ALDH1A1 (0.48) | PKMPOLBSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1476493-B1 | CURABLE COMPOSITIONS CONTAINING BENZOXAZINE | HENKEL AG & CO KGAA (DE) | 2011-03-09 | — | — | EP | disclosed |
| WO-2009067112-A1 | REDOX-INDUCED CATIONICALLY POLYMERIZABLE COMPOSITIONS WITH LOW CURE TEMPERATURE | HENKEL AG & CO. KGAA (DE) | 2009-05-28 | — | — | WO | disclosed |