Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763213 | 0.89 | ALDH1A1 (0.44) | LMNAKMT2AHTTMAPTALDH1A1 | |
| SCHEMBL9763444 | 0.82 | SMN1; SMN2 (0.39) | KMT2AMAPTALDH1A1KDM4ETSHR | |
| SCHEMBL9878999 | 0.78 | LMNA (0.50) | LMNAKMT2AHTTMAPTALDH1A1 | |
| SCHEMBL8795503 | 0.76 | LMNA (0.45) | LMNAKMT2AHTTMAPTALDH1A1 | |
| SCHEMBL9814539 | 0.75 | ALDH1A1 (0.50) | LMNAKMT2AHTTMAPTALDH1A1 | |
| SCHEMBL7589406 | 0.74 | MAPT (0.51) | LMNAKMT2AHTTMAPTL3MBTL1 | |
| SCHEMBL10668838 | 0.72 | ALDH1A1 (0.44) | LMNAKMT2AHTTMAPTALDH1A1 | |
| SCHEMBL17938209 | 0.69 | BMI1 (0.40) | KMT2AHTTALDH1A1L3MBTL1TSHR | |
| SCHEMBL5516786 | 0.68 | ALDH1A1 (0.42) | LMNAKMT2AHTTMAPTALDH1A1 | |
| SCHEMBL43388 | 0.68 | ALDH1A1 (0.42) | LMNAKMT2AHTTMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63141971-A | — | — | None | — | — | JP | disclosed |
| EP-0270111-B1 | PYRIMIDINE DERIVATIVES AND AGRICULTURAL OR HORTICULTURAL FUNGICIDAL COMPOSITION CONTANING THE SAME | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-05-15 | — | — | EP | disclosed |
| US-4992438-A | Pyrimidine derivatives, process for preparing the same and agricultural or horticultural fungicidal composition containing the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1991-02-12 | — | — | US | disclosed |
| JP-S63141971-A | PYRIMIDINE DERIVATIVE AND GERMICIDE FOR AGRICULTURE AND HORTICULTURE | KUMIAI CHEM IND CO LTD | 1988-06-14 | — | — | JP | disclosed |
| EP-0270111-A1 | Pyrimidine derivatives and agricultural or horticultural fungicidal composition contaning the same | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-06-08 | — | — | EP | disclosed |