SCHEMBL9763385

SCHEMBL9763385

Cc1cc(S(=O)(=O)Cl)c(O)c2c1CCC2=O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.34
HSP90AB1 P08238 1/20 0.34
KDM4E B2RXH2 3/20 0.33
MEN1 O00255 2/20 0.33
MAPT P10636 2/20 0.33
KMT2A Q03164 2/20 0.33
USP2 O75604 1/20 0.33
MAOA P21397 3/20 0.32
CYP2C9 P11712 1/20 0.32
ALDH1A1 P00352 2/20 0.31
HPGD P15428 2/20 0.31
RECQL P46063 1/20 0.31
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31
RXRG P48443 1/20 0.31
GLA P06280 1/20 0.30
GAA P10253 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
ELAVL1 Q15717 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10667632 0.79 L3MBTL1 (0.46) KDM4EMEN1KMT2ACYP2C9ALDH1A1
SCHEMBL9579461 0.78 MAOA (0.47) HSP90AA1HSP90AB1KDM4EMEN1MAPT
SCHEMBL10669038 0.77 MAOA (0.51) HSP90AA1HSP90AB1KDM4EMEN1MAPT
SCHEMBL10665080 0.73 HSP90AA1 (0.35) HSP90AA1HSP90AB1KDM4EMEN1MAPT
SCHEMBL18352412 0.71 MAOA (0.42) HSP90AA1HSP90AB1KDM4EMEN1MAPT
SCHEMBL10667436 0.71 HSP90AA1 (0.33) HSP90AA1HSP90AB1KDM4EMEN1MAPT
SCHEMBL10664714 0.70 MAOA (0.40) HSP90AA1HSP90AB1KDM4EMEN1MAPT
SCHEMBL10936571 0.69 TXNRD1 (0.36) KDM4EMEN1MAPTKMT2AUSP2
SCHEMBL10667715 0.69 MAOA (0.56) HSP90AA1KDM4EMEN1MAPTKMT2A
SCHEMBL10664901 0.68 ALDH1A1 (0.38) HSP90AA1HSP90AB1KDM4EMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3128340-A None JP disclosed
JP-H03128340-A INDANE DERIVATIVE OTSUKA PHARMACEUT CO LTD 1991-05-31 JP disclosed
US-4792628-A ANTIOXIDANTS, ANTIINFLAMMATORY AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1988-12-20 US disclosed