Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CDC25C | P30307 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9574188 | 0.84 | ADRB2 (0.50) | CHRM2MEN1KMT2AKCNH2TSHR | |
| SCHEMBL9763372 | 0.82 | CHRM2 (0.64) | CHRM2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL9574250 | 0.79 | ADRB2 (0.53) | CHRM2MEN1KMT2AKCNH2TSHR | |
| SCHEMBL3668267 | 0.79 | ADRB2 (0.55) | MEN1KMT2AKCNH2TSHRADRB2 | |
| SCHEMBL10477830 | 0.78 | CHRM2 (0.64) | CHRM2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL9763519 | 0.77 | ADRB2 (0.39) | MEN1KMT2AKCNH2TSHRADRB2 | |
| SCHEMBL9763701 | 0.73 | CHRM2 (0.51) | CHRM2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL28884060 | 0.73 | KMT2A (0.65) | CHRM2MEN1KMT2AKCNH2TSHR | |
| Hydrochloric Acid SCHEMBL28374440 | 0.72 | KMT2A (0.64) | CHRM2MEN1KMT2AKCNH2TSHR | |
| SCHEMBL9165352 | 0.72 | TSHR (0.55) | CHRM2KCNH2TSHREPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990505-A | Treating asthma, bronchitis; adrenergic stimulants | GLAXO GROUP LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |