Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 8/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | FPR3 | P25089 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763777 | 0.83 | SIGMAR1 (0.49) | FFAR4BCHEMAPTNPC1SMN1; SMN2 | |
| SCHEMBL9574188 | 0.82 | ADRB2 (0.50) | ADRB2ADRB1ADRB3KDM4EALOX15 | |
| SCHEMBL9763258 | 0.82 | SIGMAR1 (0.50) | FFAR4BCHEMAPTNPC1SMN1; SMN2 | |
| SCHEMBL3668267 | 0.78 | ADRB2 (0.55) | ADRB2ADRB1ADRB3KDM4EALOX15 | |
| SCHEMBL9574250 | 0.78 | ADRB2 (0.53) | ADRB2ADRB1ADRB3KDM4EALOX15 | |
| SCHEMBL9763489 | 0.77 | CHRM2 (0.50) | ADRB2ADRB1ADRB3KDM4EALOX15 | |
| SCHEMBL10762464 | 0.75 | ALDH1A1 (0.38) | ADRB2ADRB1ADRB3KDM4EALOX15 | |
| SCHEMBL9764527 | 0.73 | SIGMAR1 (0.48) | GAABCHEMAPTNPC1HTT | |
| SCHEMBL10464040 | 0.72 | HRH3 (0.48) | SLC6A2HTR2CSLC6A4HTR7SLC6A3 | |
| SCHEMBL9762755 | 0.71 | HRH3 (0.46) | SLC6A2HTR2CSLC6A4HTR7SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990505-A | Treating asthma, bronchitis; adrenergic stimulants | GLAXO GROUP LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |