Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 10/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14228293 | 0.85 | CRHR1 (0.47) | CRHR1ALDH1A1KDM4EHPGD | |
| SCHEMBL10111222 | 0.79 | CRHR1 (0.41) | CRHR1ALDH1A1 | |
| SCHEMBL13343452 | 0.76 | ALDH1A1 (0.43) | CRHR1ALDH1A1MEN1TP53KMT2A | |
| SCHEMBL29381565 | 0.76 | CRHR1 (0.42) | CRHR1MEN1KMT2A | |
| SCHEMBL27410101 | 0.75 | CRHR1 (0.41) | CRHR1ALDH1A1 | |
| SCHEMBL27496394 | 0.75 | CRHR1 (0.40) | CRHR1ALDH1A1KDM4ETP53SMN1; SMN2 | |
| SCHEMBL10348155 | 0.74 | ALDH1A1 (0.42) | CRHR1ALDH1A1KDM4ETP53HTT | |
| SCHEMBL11797024 | 0.74 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDMEN1TP53 | |
| SCHEMBL7794555 | 0.72 | CYP2C19 (0.44) | CRHR1ALDH1A1HPGDHTTLMNA | |
| SCHEMBL10898445 | 0.72 | HPGD (0.42) | ALDH1A1KDM4EHPGDMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997918-A | Benzthiazolium azo dyes | CIBA-GEIGY CORPORATION (US) | 1991-03-05 | — | — | US | disclosed |
| EP-0105031-A2 | Cationic azo dyestuffs | CIBA-GEIGY AG (CH) | 1984-04-04 | — | — | EP | disclosed |