SCHEMBL9763751

SCHEMBL9763751

C=CCN(CCC[Si](OC)(OC)OC)C(=O)C=C

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 2/20 0.37
ZDHHC2 Q9UIJ5 1/20 0.37
ALDH1A1 P00352 3/20 0.37
LMNA P02545 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
KCNH2 Q12809 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4316811 0.90 ZDHHC20 (0.41) ZDHHC20ZDHHC2
SCHEMBL907327 0.86 ZDHHC20 (0.41) ZDHHC20ZDHHC2LMNA
SCHEMBL7089998 0.86 ALDH1A1 (0.38) ALDH1A1LMNANPSR1KCNH2SMN1; SMN2
SCHEMBL9763753 0.82 ALDH1A1 (0.35) ALDH1A1LMNANPSR1
SCHEMBL23303408 0.82 ZDHHC20 (0.35) ZDHHC20ZDHHC2
SCHEMBL19610470 0.79 ALDH1A1 (0.50) ZDHHC20ZDHHC2ALDH1A1LMNASMN1; SMN2
SCHEMBL15617260 0.79 ALDH1A1 (0.50) ZDHHC20ZDHHC2ALDH1A1LMNASMN1; SMN2
SCHEMBL907561 0.79 ZDHHC20 (0.30) ZDHHC20ZDHHC2
SCHEMBL11863639 0.78 ALDH1A1 (0.33) ALDH1A1LMNAKCNH2SMN1; SMN2
SCHEMBL9764022 0.78 ZDHHC20 (0.38) ZDHHC20ZDHHC2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2107650-A None JP disclosed
US-5075459-A Organosilicon compound TOSHIBA SILICONE CO., LTD. (JP) 1991-12-24 US disclosed
US-4990641-A Crosslinking agent, modifier for composites TOSHIBA SILICONE CO., LTD. (JP) 1991-02-05 US disclosed
JP-H02107650-A TREATING AGENT FOR INORGANIC SILICEOUS FILLER TOSHIBA SILICONE CO LTD 1990-04-19 JP disclosed