Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763751 | 0.86 | ZDHHC20 (0.37) | ALDH1A1LMNANPSR1KCNH2SMN1; SMN2 | |
| SCHEMBL3678319 | 0.84 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL9194761 | 0.84 | LMNA (0.32) | LMNA | |
| SCHEMBL9763753 | 0.83 | ALDH1A1 (0.35) | ALDH1A1LMNANPSR1 | |
| SCHEMBL9299945 | 0.82 | — | — | |
| SCHEMBL3844670 | 0.80 | CA12 (0.36) | ALDH1A1LMNA | |
| SCHEMBL11863639 | 0.79 | ALDH1A1 (0.33) | ALDH1A1LMNATDP1KCNH2SMN1; SMN2 | |
| SCHEMBL9452183 | 0.79 | LMNA (0.32) | LMNA | |
| SCHEMBL4316811 | 0.78 | ZDHHC20 (0.41) | — | |
| SCHEMBL28036930 | 0.78 | LMNA (0.36) | ALDH1A1LMNANPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991698-B1 | SILICONE OLIGOMERS AND CURABLE COMPOSITIONS CONTAINING SAME | MOMENTIVE PERFORMANCE MAT INC (US) | 2012-10-24 | — | — | EP | disclosed |
| US-6515043-B2 | Surface treatment of filler | CROMPTON CORPORATION | 2003-02-04 | — | — | US | disclosed |
| US-6395856-B1 | CURABLE POLYSILOXANES FOR PROTECTIVE COATINGS FOR WIRES | CROMPTON CORPORATION | 2002-05-28 | — | — | US | disclosed |
| US-20010021761-A1 | Silicone oligomers with heigher alkoxy groups | MOMENTIVE PERFORMANCE MATERIALS INC. | 2001-09-13 | — | — | US | disclosed |
| US-6207783-B1 | UNDERGROUND INSULATION | CROMPTON CORPORATION | 2001-03-27 | — | — | US | disclosed |
| EP-0991698-A1 | SILICONE OLIGOMERS AND CURABLE COMPOSITIONS CONTAINING SAME | CK WITCO CORPORATION (US) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999054386-A1 | SILICONE OLIGOMERS AND CURABLE COMPOSITIONS CONTAINING SAME | WITCO CORPORATION (US) | 1999-10-28 | — | — | WO | disclosed |