SCHEMBL9763753

SCHEMBL9763753

C=CCN(CCC[Si](OC)(OC)OC)C(=O)C(=C)C

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
LMNA P02545 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1614987 0.88 ALDH1A1 (0.30) ALDH1A1
SCHEMBL8827898 0.86 ALDH1A1 (0.33) ALDH1A1
SCHEMBL907240 0.83 CA12 (0.33) LMNA
SCHEMBL7089998 0.83 ALDH1A1 (0.38) ALDH1A1LMNANPSR1
SCHEMBL9763751 0.82 ZDHHC20 (0.37) ALDH1A1LMNANPSR1
SCHEMBL9764168 0.82 ALDH1A1 (0.37) ALDH1A1
SCHEMBL9764039 0.79 ALDH1A1 (0.36) ALDH1A1
SCHEMBL9764556 0.79 ALDH1A1 (0.36) ALDH1A1
SCHEMBL24063928 0.78 CA12 (0.41) ALDH1A1
SCHEMBL134107 0.78 ALDH1A1 (0.41) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4990641-A Crosslinking agent, modifier for composites TOSHIBA SILICONE CO., LTD. (JP) 1991-02-05 US disclosed
US-4927951-A (METH)ACRYLAMIDE GROUP CONTAINING SILOXANES TOSHIBA SILICONE CO., LTD. (JP) 1990-05-22 US disclosed