Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GNRHR | P30968 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764105 | 0.79 | MEN1 (0.39) | ALDH1A1LMNANPSR1KDM4EKMT2A | |
| SCHEMBL12758829 | 0.78 | ALDH1A1 (0.44) | ALDH1A1LMNANPSR1KDM4EGAA | |
| SCHEMBL9756781 | 0.76 | HMGCR (0.49) | — | |
| SCHEMBL9764130 | 0.73 | LMNA (0.34) | ALDH1A1LMNANPSR1KDM4EGAA | |
| SCHEMBL9697139 | 0.70 | ALDH1A1 (0.41) | ALDH1A1LMNAKDM4EGAAKMT2A | |
| SCHEMBL12758837 | 0.69 | ALDH1A1 (0.46) | ALDH1A1KDM4EGAAKMT2AMEN1 | |
| SCHEMBL9756864 | 0.68 | HMGCR (0.38) | ALDH1A1LMNANPSR1KDM4EKMT2A | |
| SCHEMBL9756865 | 0.68 | HMGCR (0.38) | ALDH1A1LMNANPSR1KDM4EKMT2A | |
| SCHEMBL10335177 | 0.66 | KMT2A (0.36) | ALDH1A1LMNAKDM4EGAAKMT2A | |
| SCHEMBL5805243 | 0.66 | HMGCR (0.52) | ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5032590-A | Substituted hydroxylamines | BAYER AKTIENGESELLSCHAFT (DE) | 1991-07-16 | — | — | US | disclosed |
| US-4968681-A | Substituted hydroxylamines | BAYER AKTIENGESELLSCHAFT (DE) | 1990-11-06 | — | — | US | disclosed |
| EP-0317845-A2 | Substituted hydroxyl amines | BAYER AG (DE) | 1989-05-31 | — | — | EP | disclosed |