Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.31 |
| ▸ | LIPE | Q05469 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LDHA | P00338 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | LDHB | P07195 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764105 | 0.84 | MEN1 (0.39) | LMNAALDH1A1MEN1KMT2APTGS2 | |
| SCHEMBL9764098 | 0.73 | ALDH1A1 (0.51) | LMNAALDH1A1MEN1KMT2APTGS2 | |
| SCHEMBL9756864 | 0.72 | HMGCR (0.38) | LMNAALDH1A1MEN1KMT2APTGS2 | |
| SCHEMBL9756865 | 0.72 | HMGCR (0.38) | LMNAALDH1A1MEN1KMT2APTGS2 | |
| SCHEMBL9697139 | 0.69 | ALDH1A1 (0.41) | LMNAALDH1A1MEN1MAPK1HTT | |
| SCHEMBL9696399 | 0.68 | KMT2A (0.45) | LMNAALDH1A1MEN1HTTKMT2A | |
| SCHEMBL10335177 | 0.65 | KMT2A (0.36) | LMNAALDH1A1MEN1KMT2APTGS2 | |
| SCHEMBL10304736 | 0.64 | PTGS2 (0.40) | ALDH1A1TSHRPTGS2MAPTKDM4E | |
| SCHEMBL9750845 | 0.63 | HMGCR (0.56) | LMNAALDH1A1KMT2APTGS2 | |
| SCHEMBL9518289 | 0.63 | HMGCR (0.47) | LMNAALDH1A1MEN1KMT2APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5032590-A | Substituted hydroxylamines | BAYER AKTIENGESELLSCHAFT (DE) | 1991-07-16 | — | — | US | disclosed |
| US-4968681-A | Substituted hydroxylamines | BAYER AKTIENGESELLSCHAFT (DE) | 1990-11-06 | — | — | US | disclosed |
| EP-0317845-A2 | Substituted hydroxyl amines | BAYER AG (DE) | 1989-05-31 | — | — | EP | disclosed |