Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764095 | 0.87 | ALDH1A1 (0.43) | ALDH1A1LMNAKDM4ETDP1L3MBTL1 | |
| SCHEMBL9764313 | 0.81 | PTGS2 (0.43) | ALDH1A1LMNAKDM4ETDP1L3MBTL1 | |
| SCHEMBL9756726 | 0.75 | PTGS2 (0.39) | ALDH1A1KDM4ETDP1L3MBTL1 | |
| SCHEMBL9756723 | 0.75 | PTGS2 (0.39) | ALDH1A1KDM4ETDP1L3MBTL1 | |
| SCHEMBL9658354 | 0.73 | ALDH1A1 (0.41) | ALDH1A1LMNAKDM4EARTDP1 | |
| SCHEMBL9764185 | 0.72 | KDM4E (0.48) | ALDH1A1KDM4EARTDP1L3MBTL1 | |
| SCHEMBL12758829 | 0.72 | ALDH1A1 (0.44) | ALDH1A1LMNAKDM4ENPSR1SMN1; SMN2 | |
| SCHEMBL13302411 | 0.70 | ALDH1A1 (0.39) | ALDH1A1LMNANPSR1 | |
| SCHEMBL7142622 | 0.69 | MAPT (0.52) | ALDH1A1LMNAKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL10821003 | 0.68 | ALDH1A1 (0.77) | ALDH1A1LMNAKDM4ENPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5032590-A | Substituted hydroxylamines | BAYER AKTIENGESELLSCHAFT (DE) | 1991-07-16 | — | — | US | disclosed |
| US-4968681-A | Substituted hydroxylamines | BAYER AKTIENGESELLSCHAFT (DE) | 1990-11-06 | — | — | US | disclosed |
| EP-0317845-A2 | Substituted hydroxyl amines | BAYER AG (DE) | 1989-05-31 | — | — | EP | disclosed |