Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CYP51A1 | Q16850 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764429 | 0.94 | ADRB2 (0.41) | ADRB2SLC2A1NR1H3ADRB1BCHE | |
| SCHEMBL9764456 | 0.94 | ADRB2 (0.41) | ADRB2SLC2A1NR1H3ADRB1BCHE | |
| SCHEMBL9764389 | 0.91 | ADRB2 (0.39) | ADRB2SLC2A1NR1H3ADRB1BCHE | |
| SCHEMBL9764371 | 0.91 | ADRB2 (0.41) | ADRB2SLC2A1NR1H3ADRB1BCHE | |
| SCHEMBL9764694 | 0.89 | NR1H3 (0.45) | ADRB2NR1H3BCHE | |
| SCHEMBL10346957 | 0.88 | KDM4E (0.40) | NR1H3BCHESLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL4950922 | 0.88 | ADRB2 (0.44) | ADRB2ADRB1BCHECYP51A1CA12 | |
| SCHEMBL10423748 | 0.88 | ADRB2 (0.41) | ADRB2NR1H3ADRB1 | |
| SCHEMBL9764242 | 0.87 | MC4R (0.39) | ADRB2CA12CA1CA2CA4 | |
| SCHEMBL9321535 | 0.86 | MAOB (0.37) | ADRB2NR1H3ADRB1BCHESLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006556-A | Dichloroaniline derivatives for the therapy or prophylaxysis of a disease associated with reversible airway obstruction | GLAXO GROUP LIMITED (GB) | 1991-04-09 | — | — | US | disclosed |
| US-4943591-A | TREATMENT OF ASTHMA AND BRONCHITIS | GLAXO GROUP LIMITED (GB) | 1990-07-24 | — | — | US | disclosed |
| EP-0181709-A1 | Dichloroaniline Derivatives | GLAXO GROUP LIMITED (GB) | 1986-05-21 | — | — | EP | disclosed |