Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HMGCR | P04035 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.37 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | CDC25A | P30304 | 1/20 | 0.34 |
| ▸ | CDC25C | P30307 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9751010 | 0.78 | HMGCR (0.49) | KDM4EALDH1A1TDP1L3MBTL1HMGCR | |
| SCHEMBL9518177 | 0.76 | HMGCR (0.47) | HMGCR | |
| SCHEMBL9751046 | 0.75 | HMGCR (0.55) | ALDH1A1HMGCRMET | |
| SCHEMBL9750967 | 0.74 | HMGCR (0.47) | KDM4EHMGCRMEN1KMT2A | |
| SCHEMBL22188201 | 0.73 | KDM4E (0.42) | KDM4EALDH1A1TDP1L3MBTL1HMGCR | |
| SCHEMBL6493537 | 0.73 | HMGCR (0.45) | HMGCRCYP2C9PTGDRPTGDR2 | |
| SCHEMBL10506766 | 0.72 | HMGCR (0.39) | HMGCRCDC25ACDC25C | |
| SCHEMBL29941711 | 0.72 | GSK3B (0.48) | MEN1KMT2ACDC25ACDC25CCYP2C9 | |
| SCHEMBL1878132 | 0.72 | GSK3B (0.48) | MEN1KMT2ACDC25ACDC25CCYP2C9 | |
| SCHEMBL5731708 | 0.72 | ALDH1A1 (0.50) | KDM4EALDH1A1MEN1KMT2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5032590-A | Substituted hydroxylamines | BAYER AKTIENGESELLSCHAFT (DE) | 1991-07-16 | — | — | US | disclosed |
| US-4968681-A | Substituted hydroxylamines | BAYER AKTIENGESELLSCHAFT (DE) | 1990-11-06 | — | — | US | disclosed |
| CN-1033991-A | SUBSTITUTED HYDROXYLAMINES | BAYER AG (DE) | 1989-07-19 | — | — | CN | disclosed |
| EP-0317845-A2 | Substituted hydroxyl amines | BAYER AG (DE) | 1989-05-31 | — | — | EP | disclosed |
| EP-0300278-A2 | Process for the preparation of 2-substituted pyrroles | BAYER AG (DE) | 1989-01-25 | — | — | EP | disclosed |