Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.37 |
| ▸ | RORC | P51449 | 4/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764279 | 0.85 | NR1H3 (0.35) | KDM4E | |
| SCHEMBL9764538 | 0.83 | HPGD (0.35) | HTTKDM4EALDH1A1MAPTPOLB | |
| SCHEMBL9764548 | 0.83 | KCNH2 (0.33) | KDM4EKCNH2 | |
| SCHEMBL10466615 | 0.82 | NR1H3 (0.34) | KDM4EKCNH2MEN1KMT2A | |
| SCHEMBL10468115 | 0.81 | RORC (0.35) | RORCLMNAKDM4EALDH1A1KCNH2 | |
| SCHEMBL10468372 | 0.81 | NR1H3 (0.33) | LMNAKDM4EALDH1A1MAPT | |
| SCHEMBL9319139 | 0.80 | MAOB (0.38) | ALDH1A1 | |
| SCHEMBL9764569 | 0.80 | SNCA (0.38) | ALDH1A1GAAKMT2A | |
| SCHEMBL10466931 | 0.80 | NR1H3 (0.33) | KDM4E | |
| SCHEMBL10465464 | 0.79 | MAOB (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5006556-A | Dichloroaniline derivatives for the therapy or prophylaxysis of a disease associated with reversible airway obstruction | GLAXO GROUP LIMITED (GB) | 1991-04-09 | — | — | US | disclosed |
| US-4943591-A | TREATMENT OF ASTHMA AND BRONCHITIS | GLAXO GROUP LIMITED (GB) | 1990-07-24 | — | — | US | disclosed |