Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 5/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 4/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 3/20 | 0.31 |
| ▸ | ACHE | P22303 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10468372 | 0.88 | NR1H3 (0.33) | NR1H3SLC2A1NR1H2BCHEACHE | |
| SCHEMBL10466933 | 0.84 | NR1H3 (0.36) | NR1H3SLC2A1NR1H2EGLN1MAOB | |
| SCHEMBL10466931 | 0.84 | NR1H3 (0.33) | NR1H3SLC2A1KDM4E | |
| SCHEMBL9764279 | 0.84 | NR1H3 (0.35) | NR1H3SLC2A1MAOBBCHEACHE | |
| SCHEMBL9764538 | 0.83 | HPGD (0.35) | NR1H3MAOBBCHEACHEKDM4E | |
| SCHEMBL10466598 | 0.83 | MMP13 (0.34) | NR1H3SLC2A1MAOBBCHEACHE | |
| SCHEMBL9319139 | 0.82 | MAOB (0.38) | NR1H3MAOB | |
| SCHEMBL9764422 | 0.82 | LTA4H (0.37) | KCNH2KDM4EMEN1KMT2A | |
| SCHEMBL10468115 | 0.81 | RORC (0.35) | NR1H3SLC2A1MAOBKCNH2KDM4E | |
| SCHEMBL9764548 | 0.81 | KCNH2 (0.33) | NR1H3KCNH2BCHEACHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4921867-A | Pyridine compounds useful for therapy or prophylaxis of a disease associated with airway obstruction | GLAXO GROUP LIMITED (GB) | 1990-05-01 | — | — | US | disclosed |