Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.30 |
| ▸ | SELE | P16581 | 1/20 | 0.30 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8852216 | 0.87 | KDM4E (0.36) | KDM4EGABRA1GABRB2POLBJAK1 | |
| SCHEMBL486060 | 0.83 | GABRA1 (0.40) | KDM4EGABRA1GABRB2POLBJAK1 | |
| SCHEMBL14058648 | 0.80 | KDM4E (0.42) | KDM4EMAPK1PARP1MAPT | |
| SCHEMBL7870129 | 0.78 | GABRA1 (0.44) | KDM4EGABRA1GABRB2JAK1TYK2 | |
| SCHEMBL8824319 | 0.78 | GABRA1 (0.44) | KDM4EGABRA1GABRB2JAK1TYK2 | |
| SCHEMBL18915 | 0.78 | GAA (0.38) | KDM4EGABRA1GABRB2POLBPTGDR | |
| SCHEMBL28618628 | 0.77 | GABRA1 (0.43) | KDM4EGABRA1GABRB2JAK1TYK2 | |
| Water SCHEMBL3696709 | 0.77 | GAA (0.37) | KDM4EGABRA1GABRB2POLBPTGDR | |
| SCHEMBL4316249 | 0.75 | MAPK1 (0.36) | KDM4EGABRA1GABRB2POLBJAK1 | |
| SCHEMBL1349070 | 0.74 | GAA (0.39) | KDM4EGABRA1GABRB2POLBPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3143942-A | — | — | None | — | — | JP | disclosed |
| US-20120302704-A1 | COPOLYMER COMPOSED OF A POLYPHENYLENE AND A FLEXIBLE CHAIN COMPONENT | ROBERT BOSCH GMBH (DE) | 2012-11-29 | — | — | US | disclosed |
| JP-H03143942-A | RIGID VINYL CHLORIDE RESIN COMPOSITION | SEKISUI CHEM CO LTD | 1991-06-19 | — | — | JP | disclosed |