Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | JAK3 | P52333 | 2/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NNMT | P40261 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TEC | P42680 | 1/20 | 0.32 |
| ▸ | TXK | P42681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4558591 | 0.80 | GABRA1 (0.36) | MAPK1KDM4EHSD17B10GABRA1GABRB2 | |
| SCHEMBL10911271 | 0.79 | MAPK1 (0.37) | MAPK1KDM4EHSD17B10GABRA1GABRB2 | |
| SCHEMBL1018603 | 0.77 | NNMT (0.47) | MAPK1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL29889389 | 0.77 | NNMT (0.47) | MAPK1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL27377658 | 0.77 | NNMT (0.36) | KDM4EHSD17B10KMT2ANNMTSIRT3 | |
| Ammonia Solution, Strong SCHEMBL6013986 | 0.75 | CES2 (0.41) | MEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL27544857 | 0.75 | GABRA1 (0.36) | MAPK1KDM4EHSD17B10GABRA1GABRB2 | |
| SCHEMBL7738384 | 0.75 | SRC (0.45) | MAPK1GABRA1GABRB2MEN1KMT2A | |
| SCHEMBL486060 | 0.75 | GABRA1 (0.40) | MAPK1KDM4EJAK3JAK1TYK2 | |
| SCHEMBL9764452 | 0.75 | KDM4E (0.36) | MAPK1KDM4EJAK3JAK1TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9180209-B2 | Non-peptidic quenched fluorescent imaging probes | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2015-11-10 | — | — | US | disclosed |
| US-20140140930-A1 | NON-PEPTIDIC QUENCHED FLUORESCENT IMAGING PROBES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2014-05-22 | — | — | US | disclosed |
| US-20090215893-A1 | Parakeratosis inhibitor, pore-shrinking agent,or rough skin preventing/ameliorating agent, and external composition for skin | SHISEIDO COMPANY LTD (JP) | 2009-08-27 | — | — | US | disclosed |
| EP-1884230-A1 | PARAKERATOSIS INHIBITOR, PORE-SHRINKING AGENT OR AGENT FOR PREVENTING/AMELIORATING ROUGH SKIN AND EXTERNAL COMPOSITION FOR SKIN | Shiseido Company, Limited (JP) | 2008-02-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140140930-A1 | NON-PEPTIDIC QUENCHED FLUORESCENT IMAGING PROBES | CTSZ, CTSS, CTSF | MAPK1 988/4885KDM4E 1385/4885JAK3 3090/4885 |
| US-20090215893-A1 | Parakeratosis inhibitor, pore-shrinking agent,or rough skin preventing/ameliorating agent, and external composition for skin | CUTA, STOM, MTOR | MAPK1 875/4885KDM4E 1576/4885JAK3 3032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.