Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MITF | O75030 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | LTA4H | P09960 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10011199 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HTTLMNACYP2D6CYP2C9 | |
| SCHEMBL10008027 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HTTCYP2C9CYP3A4KDM4E | |
| SCHEMBL9764604 | 0.79 | HRH3 (0.58) | ALDH1A1HTTLMNAKDM4EMITF | |
| SCHEMBL9174306 | 0.77 | PTPN1 (0.70) | HPGDCYP3A4ALOX15PTPN1PTPN2 | |
| SCHEMBL9804555 | 0.77 | PTPN1 (0.70) | HPGDCYP3A4ALOX15PTPN1PTPN2 | |
| SCHEMBL29799377 | 0.76 | PRMT6 (0.51) | ALDH1A1CYP2D6CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL9764649 | 0.75 | LTA4H (0.49) | ALDH1A1HPGDLMNACYP2D6CYP2C9 | |
| SCHEMBL11209438 | 0.75 | PTPN1 (0.68) | HPGDCYP3A4ALOX15PTPN1PTPN2 | |
| SCHEMBL30275949 | 0.75 | KDM4E (0.56) | ALDH1A1HTTLMNACYP2D6CYP2C9 | |
| SCHEMBL9764759 | 0.75 | CACNA1B (0.57) | ALDH1A1CYP2D6CYP2C9L3MBTL1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5059620-A | Antiarrhythmia agents | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-10-22 | — | — | US | disclosed |
| US-4923873-A | ANTIARRHYTHMIA AGENTS; SIDE EFFECT REDUCTION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-05-08 | — | — | US | disclosed |
| US-4755527-A | Aryl substituted aminomethyl benzene derivatives | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-07-05 | — | — | US | disclosed |
| US-4748184-A | Aryl substituted aminomethyl benzene derivatives having antiarrhythmic utility | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-05-31 | — | — | US | disclosed |
| US-4562201-A | ANTIARRHYTHMIA AGNETS | AMERICAN HOSPITAL SUPPLY CORPORATION (US) | 1985-12-31 | — | — | US | disclosed |
| EP-0113778-A4 | ARYL SUBSTITUTED AMINOMETHYL BENZENE DERIVATIVES USEFUL AS ANTIARRHYTHMIC AGENTS. | AMERICAN HOSPITAL SUPPLY CORP (US) | 1985-06-06 | — | — | EP | disclosed |
| EP-0113778-A1 | ARYL SUBSTITUTED AMINOMETHYL BENZENE DERIVATIVES USEFUL AS ANTIARRHYTHMIC AGENTS. | AMERICAN HOSPITAL SUPPLY CORP (US) | 1984-07-25 | — | — | EP | disclosed |
| WO-1984000545-A1 | ARYL SUBSTITUTED AMINOMETHYL BENZENE DERIVATIVES USEFUL AS ANTIARRHYTHMIC AGENTS | AMERICAN HOSPITAL SUPPLY CORP (US) | 1984-02-16 | — | — | WO | disclosed |