Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 11/20 | 0.58 |
| ▸ | GRIN2B | Q13224 | 11/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9440112 | 0.90 | KDM4E (0.58) | GRIN1GRIN2BKDM4EALDH1A1LMNA | |
| SCHEMBL7907147 | 0.86 | KDM4E (0.58) | GRIN1GRIN2BKDM4EALDH1A1LMNA | |
| SCHEMBL10673 | 0.82 | KDM4E (0.54) | GRIN1GRIN2BKDM4EALDH1A1LMNA | |
| SCHEMBL8763454 | 0.81 | GRIN1 (0.65) | GRIN1GRIN2BKDM4EALDH1A1LMNA | |
| SCHEMBL9028983 | 0.80 | HPGD (0.61) | GRIN1GRIN2BKDM4EALDH1A1LMNA | |
| SCHEMBL8868256 | 0.80 | KDM4E (0.61) | GRIN1GRIN2BKDM4EALDH1A1LMNA | |
| SCHEMBL5726108 | 0.80 | HPGD (0.57) | GRIN1GRIN2BKDM4EALDH1A1LMNA | |
| SCHEMBL9387334 | 0.79 | HPGD (0.65) | GRIN1GRIN2BKDM4EALDH1A1LMNA | |
| SCHEMBL657740 | 0.79 | ALDH1A1 (0.64) | GRIN1GRIN2BKDM4EALDH1A1LMNA | |
| SCHEMBL10750177 | 0.79 | ALDH1A1 (0.59) | GRIN1GRIN2BKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026712-A | Novel imidazo[1,5-a]pyridines, useful as cardiovascular and CNS agents | SCHERING AG (DE) | 1991-06-25 | — | — | US | disclosed |