Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1422207 | 0.84 | ALDH1A1 (0.63) | HPGDKDM4EALDH1A1LMNAHTT | |
| SCHEMBL11195052 | 0.84 | HPGD (0.63) | HPGDKDM4EALDH1A1LMNAHTT | |
| SCHEMBL9440112 | 0.83 | KDM4E (0.58) | HPGDKDM4EALDH1A1LMNAHTT | |
| SCHEMBL4149990 | 0.82 | HPGD (0.61) | HPGDKDM4EALDH1A1LMNAHTT | |
| SCHEMBL397628 | 0.81 | HPGD (0.56) | HPGDKDM4EALDH1A1LMNAHTT | |
| SCHEMBL23647680 | 0.81 | SMN1; SMN2 (0.59) | HPGDKDM4EALDH1A1LMNAHTT | |
| SCHEMBL1574068 | 0.81 | KDM4E (0.65) | HPGDKDM4EALDH1A1LMNAHTT | |
| SCHEMBL13545194 | 0.81 | KDM4E (0.59) | HPGDKDM4EALDH1A1LMNAHTT | |
| SCHEMBL27440295 | 0.81 | HPGD (0.65) | HPGDKDM4EALDH1A1LMNAHTT | |
| SCHEMBL9764795 | 0.80 | GRIN1 (0.58) | HPGDKDM4EALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700385-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM LABORATOIRES PHARMACEUTIQUES (FR) | 1996-03-13 | — | — | EP | disclosed |
| WO-1994027967-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM LABORATOIRES PHARMACEUTIQUES (FR) | 1994-12-08 | — | — | WO | disclosed |
| EP-0532629-A4 | — | — | 1994-03-09 | — | — | EP | disclosed |
| EP-0532629-A1 | 1-PYPERIDINYL ALKANOYLARYLSULFONAMIDE DERIVATIVES. | MERRELL DOW PHARMA (US) | 1993-03-24 | — | — | EP | disclosed |
| WO-1991018603-A1 | 1-PYPERIDINYL ALKANOYLARYLSULFONAMIDE DERIVATIVES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-12-12 | — | — | WO | disclosed |