Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT2 | O75908 | 1/20 | 0.49 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.49 |
| ▸ | UBE2M | P61081 | 1/20 | 0.48 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CASR | P41180 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11143056 | 0.90 | ALDH1A1 (0.58) | SOAT2SOAT1UBE2MDCUN1D1KMT2A | |
| SCHEMBL9192201 | 0.85 | ALDH1A1 (0.49) | ALDH1A1NPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6804058 | 0.83 | SOAT2 (0.49) | SOAT2SOAT1UBE2MDCUN1D1KMT2A | |
| SCHEMBL9723419 | 0.80 | SOAT2 (0.51) | SOAT2SOAT1KMT2ALMNAALDH1A1 | |
| SCHEMBL9679390 | 0.78 | ALDH1A1 (0.58) | SOAT2SOAT1KMT2ALMNAALDH1A1 | |
| SCHEMBL855625 | 0.78 | SOAT2 (0.52) | SOAT2SOAT1UBE2MDCUN1D1KMT2A | |
| SCHEMBL6899771 | 0.78 | SOAT1 (0.62) | SOAT2SOAT1UBE2MDCUN1D1KMT2A | |
| SCHEMBL6802990 | 0.77 | KMT2A (0.50) | SOAT2SOAT1KMT2ALMNAMEN1 | |
| SCHEMBL9765050 | 0.76 | SOAT1 (0.51) | SOAT2SOAT1UBE2MDCUN1D1KMT2A | |
| SCHEMBL9681145 | 0.76 | SOAT2 (0.56) | SOAT2SOAT1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994465-A | Antihyperlipidemic and antiatherosclerotic trisubstituted urea compounds | WARNER-LAMBERT COMPANY (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0384320-A1 | Antihyperlipidemic and anti-atherosclerotic trisubstituted urea compounds | WARNER-LAMBERT COMPANY (US) | 1990-08-29 | — | — | EP | disclosed |