Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CASR | P41180 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11142406 | 0.87 | ALDH1A1 (0.63) | ALDH1A1NPSR1TDP1CYP1A2CYP2C9 | |
| SCHEMBL9765025 | 0.85 | SOAT2 (0.49) | ALDH1A1NPSR1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9765052 | 0.80 | ICMT (0.46) | ALDH1A1NPSR1EGFRMAPK1HDAC1 | |
| SCHEMBL11144230 | 0.78 | ALDH1A1 (0.55) | ALDH1A1NPSR1TDP1POLBEGFR | |
| SCHEMBL11145395 | 0.78 | ALDH1A1 (0.56) | ALDH1A1NPSR1TDP1POLBEGFR | |
| SCHEMBL11134972 | 0.74 | KMT2A (0.51) | ALDH1A1CYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL11137929 | 0.73 | KMT2A (0.64) | ALDH1A1NPSR1TDP1POLBEGFR | |
| SCHEMBL9765058 | 0.73 | TP53 (0.46) | ALDH1A1NPSR1TDP1CYP2C19POLB | |
| SCHEMBL11139406 | 0.73 | ALDH1A1 (0.63) | ALDH1A1NPSR1POLBEGFRERBB2 | |
| SCHEMBL30734411 | 0.73 | ALDH1A1 (0.63) | ALDH1A1NPSR1POLBEGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384320-A1 | Antihyperlipidemic and anti-atherosclerotic trisubstituted urea compounds | WARNER-LAMBERT COMPANY (US) | 1990-08-29 | — | — | EP | claimed |
| EP-0500348-B1 | Disubstituted ureas and thioureas | PHARMACIA SPA (IT) | 1995-05-17 | — | — | EP | disclosed |
| US-4994465-A | Antihyperlipidemic and antiatherosclerotic trisubstituted urea compounds | WARNER-LAMBERT COMPANY (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0384320-A1 | Antihyperlipidemic and anti-atherosclerotic trisubstituted urea compounds | WARNER-LAMBERT COMPANY (US) | 1990-08-29 | — | — | EP | disclosed |