Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 5/20 | 0.51 |
| ▸ | SOAT2 | O75908 | 3/20 | 0.51 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.51 |
| ▸ | UBE2M | P61081 | 1/20 | 0.46 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.46 |
| ▸ | NMBR | P28336 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6803071 | 0.91 | UBE2M (0.46) | SOAT1SOAT2ACAT1UBE2MDCUN1D1 | |
| SCHEMBL6808919 | 0.90 | SOAT1 (0.50) | SOAT1SOAT2ACAT1UBE2MDCUN1D1 | |
| SCHEMBL9680743 | 0.87 | SOAT1 (0.51) | SOAT1SOAT2ACAT1NMBRKMT2A | |
| SCHEMBL6803622 | 0.87 | NMBR (0.45) | SOAT1SOAT2ACAT1UBE2MDCUN1D1 | |
| SCHEMBL9765058 | 0.86 | TP53 (0.46) | KMT2ALMNAALDH1A1NPSR1SLC6A2 | |
| SCHEMBL6807653 | 0.84 | SOAT1 (0.43) | SOAT1SOAT2ACAT1UBE2MDCUN1D1 | |
| SCHEMBL9765049 | 0.84 | SOAT2 (0.48) | SOAT1SOAT2ACAT1 | |
| SCHEMBL9765053 | 0.84 | NPSR1 (0.43) | KMT2ALMNAALDH1A1NPSR1SLC6A2 | |
| SCHEMBL6802078 | 0.83 | SOAT2 (0.40) | SOAT1SOAT2ACAT1UBE2MDCUN1D1 | |
| SCHEMBL11143056 | 0.83 | ALDH1A1 (0.58) | SOAT1SOAT2UBE2MDCUN1D1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0384320-A1 | Antihyperlipidemic and anti-atherosclerotic trisubstituted urea compounds | WARNER-LAMBERT COMPANY (US) | 1990-08-29 | — | — | EP | claimed |
| US-4994465-A | Antihyperlipidemic and antiatherosclerotic trisubstituted urea compounds | WARNER-LAMBERT COMPANY (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0384320-A1 | Antihyperlipidemic and anti-atherosclerotic trisubstituted urea compounds | WARNER-LAMBERT COMPANY (US) | 1990-08-29 | — | — | EP | disclosed |