Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HPGDS | O60760 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | FPR2 | P25090 | 3/20 | 0.49 |
| ▸ | CASR | P41180 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11710148 | 0.84 | CNR1 (0.62) | SMN1; SMN2RAB9AALDH1A1LMNAKDM4E | |
| SCHEMBL9765181 | 0.84 | KDM4E (0.72) | RAB9APOLBALDH1A1LMNAKDM4E | |
| SCHEMBL9753886 | 0.84 | TSHR (0.66) | RAB9APOLBALDH1A1LMNAKDM4E | |
| SCHEMBL9765215 | 0.83 | KDM4E (0.54) | SMN1; SMN2RAB9AALDH1A1LMNAKDM4E | |
| SCHEMBL9765206 | 0.80 | KDM4E (0.47) | SMN1; SMN2RAB9AALDH1A1LMNAKDM4E | |
| SCHEMBL4476091 | 0.78 | HDAC1 (0.52) | HPGDS | |
| SCHEMBL9167791 | 0.77 | KMT2A (0.60) | RAB9AALDH1A1LMNAKDM4EHPGDS | |
| SCHEMBL13853727 | 0.75 | KMT2A (0.59) | RAB9AALDH1A1LMNAKDM4EHPGDS | |
| SCHEMBL10018688 | 0.74 | KDM4E (0.58) | RAB9AALDH1A1LMNAKDM4EHPGDS | |
| SCHEMBL9765205 | 0.73 | KDM4E (0.47) | RAB9APOLBALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001141-A | N-(2-(2-oxo-1-imidazolidinyl)ethyl)-3-phenyl-urea and analogs as agents for induction of antioxidant enzymes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-03-19 | — | — | US | claimed |
| US-5001141-A | N-(2-(2-oxo-1-imidazolidinyl)ethyl)-3-phenyl-urea and analogs as agents for induction of antioxidant enzymes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-03-19 | — | — | US | disclosed |