Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | QPCT | Q16769 | 2/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9765205 | 0.84 | KDM4E (0.47) | KDM4ERAB9AKMT2ALMNAALDH1A1 | |
| SCHEMBL9765175 | 0.80 | SMN1; SMN2 (0.60) | KDM4ERAB9AKMT2AHPGDSMAPT | |
| SCHEMBL9765217 | 0.79 | KDM4E (0.51) | KDM4ERAB9AKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL9765181 | 0.76 | KDM4E (0.72) | KDM4ERAB9AKMT2AMAPTTP53 | |
| SCHEMBL11710148 | 0.74 | CNR1 (0.62) | KDM4ERAB9AKMT2AMAPTTP53 | |
| SCHEMBL9753886 | 0.74 | TSHR (0.66) | KDM4ERAB9AKMT2AMAPTLMNA | |
| SCHEMBL9765215 | 0.73 | KDM4E (0.54) | KDM4ERAB9AKMT2ATP53SMN1; SMN2 | |
| SCHEMBL9167791 | 0.73 | KMT2A (0.60) | KDM4ERAB9AKMT2AHPGDSLMNA | |
| SCHEMBL16946690 | 0.70 | S1PR1 (0.56) | RAB9AKMT2AS1PR1MAPTTP53 | |
| SCHEMBL1781567 | 0.69 | CYP2C9 (0.55) | KDM4ERAB9AKMT2AS1PR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001141-A | N-(2-(2-oxo-1-imidazolidinyl)ethyl)-3-phenyl-urea and analogs as agents for induction of antioxidant enzymes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-03-19 | — | — | US | claimed |
| US-5001141-A | N-(2-(2-oxo-1-imidazolidinyl)ethyl)-3-phenyl-urea and analogs as agents for induction of antioxidant enzymes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-03-19 | — | — | US | disclosed |