Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | FPR3 | P25089 | 2/20 | 0.40 |
| ▸ | FPR2 | P25090 | 2/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9765206 | 0.84 | KDM4E (0.47) | KDM4EKMT2ARAB9AALDH1A1RAF1 | |
| SCHEMBL9765215 | 0.80 | KDM4E (0.54) | KDM4EKMT2ARAB9AALDH1A1LMNA | |
| SCHEMBL9765217 | 0.79 | KDM4E (0.51) | KDM4EKMT2ARAB9AALDH1A1LMNA | |
| SCHEMBL9765181 | 0.76 | KDM4E (0.72) | KDM4EKMT2ARAB9AALDH1A1LMNA | |
| SCHEMBL11710148 | 0.74 | CNR1 (0.62) | KDM4EKMT2ARAB9AALDH1A1LMNA | |
| SCHEMBL9753886 | 0.74 | TSHR (0.66) | KDM4EKMT2ARAB9AALDH1A1LMNA | |
| SCHEMBL9765175 | 0.73 | SMN1; SMN2 (0.60) | KDM4EKMT2ARAB9AALDH1A1LMNA | |
| SCHEMBL9167791 | 0.70 | KMT2A (0.60) | KDM4EKMT2ARAB9AALDH1A1LMNA | |
| SCHEMBL9765199 | 0.70 | HDAC3 (0.48) | KDM4ERAB9AALDH1A1LMNATSHR | |
| SCHEMBL13853727 | 0.68 | KMT2A (0.59) | KDM4EKMT2ARAB9AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001141-A | N-(2-(2-oxo-1-imidazolidinyl)ethyl)-3-phenyl-urea and analogs as agents for induction of antioxidant enzymes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-03-19 | — | — | US | claimed |
| US-5001141-A | N-(2-(2-oxo-1-imidazolidinyl)ethyl)-3-phenyl-urea and analogs as agents for induction of antioxidant enzymes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-03-19 | — | — | US | disclosed |