Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HTR3A | P46098 | 1/20 | 0.51 |
| ▸ | FPR3 | P25089 | 2/20 | 0.50 |
| ▸ | FPR2 | P25090 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11710148 | 0.87 | CNR1 (0.62) | KDM4ELMNAALDH1A1RAB9AKMT2A | |
| SCHEMBL9753886 | 0.87 | TSHR (0.66) | KDM4ELMNAALDH1A1RAB9AKMT2A | |
| SCHEMBL9765175 | 0.84 | SMN1; SMN2 (0.60) | KDM4ELMNAALDH1A1RAB9AKMT2A | |
| SCHEMBL9765215 | 0.84 | KDM4E (0.54) | KDM4ELMNAALDH1A1RAB9AKMT2A | |
| SCHEMBL9167791 | 0.80 | KMT2A (0.60) | KDM4ELMNAALDH1A1RAB9AKMT2A | |
| SCHEMBL9765217 | 0.78 | KDM4E (0.51) | KDM4ELMNAALDH1A1RAB9AKMT2A | |
| SCHEMBL10018688 | 0.77 | KDM4E (0.58) | KDM4ELMNAALDH1A1RAB9AKMT2A | |
| SCHEMBL30415729 | 0.76 | LMNA (1.00) | KDM4ELMNAKMT2AHTR3ATSHR | |
| SCHEMBL9765205 | 0.76 | KDM4E (0.47) | KDM4ELMNAALDH1A1RAB9AKMT2A | |
| SCHEMBL9765206 | 0.76 | KDM4E (0.47) | KDM4ELMNAALDH1A1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001141-A | N-(2-(2-oxo-1-imidazolidinyl)ethyl)-3-phenyl-urea and analogs as agents for induction of antioxidant enzymes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-03-19 | — | — | US | claimed |
| US-5001141-A | N-(2-(2-oxo-1-imidazolidinyl)ethyl)-3-phenyl-urea and analogs as agents for induction of antioxidant enzymes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-03-19 | — | — | US | disclosed |