SCHEMBL9753886

SCHEMBL9753886

O=C(NCCN1CCNC1=O)Nc1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.66
KDM4E B2RXH2 4/20 0.62
KMT2A Q03164 3/20 0.59
POLB P06746 2/20 0.59
MEN1 O00255 1/20 0.59
ALDH1A1 P00352 3/20 0.58
LMNA P02545 1/20 0.58
NPSR1 Q6W5P4 1/20 0.55
RAB9A P51151 1/20 0.54
CREBBP Q92793 1/20 0.50
FPR3 P25089 2/20 0.49
FPR2 P25090 2/20 0.49
MAPT P10636 1/20 0.48
EPHX2 P34913 1/20 0.47
EPHX1 P07099 1/20 0.47
ENPP2 Q13822 1/20 0.47
PKM P14618 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9765181 0.87 KDM4E (0.72) TSHRKDM4EKMT2APOLBALDH1A1
SCHEMBL11710148 0.87 CNR1 (0.62) TSHRKDM4EKMT2AALDH1A1LMNA
SCHEMBL9765175 0.84 SMN1; SMN2 (0.60) TSHRKDM4EKMT2APOLBALDH1A1
SCHEMBL9765215 0.84 KDM4E (0.54) TSHRKDM4EKMT2AMEN1ALDH1A1
SCHEMBL9765217 0.82 KDM4E (0.51) KDM4EKMT2AMEN1ALDH1A1LMNA
SCHEMBL9167791 0.82 KMT2A (0.60) KDM4EKMT2AALDH1A1LMNARAB9A
SCHEMBL1402380 0.81 RAB9A (0.76) KDM4EKMT2AALDH1A1LMNARAB9A
SCHEMBL11706970 0.81 TSHR (0.69) TSHRKDM4EKMT2APOLBMEN1
SCHEMBL10018688 0.79 KDM4E (0.58) KDM4EKMT2AALDH1A1LMNARAB9A
SCHEMBL5654310 0.78 KMT2A (0.62) KDM4EKMT2AALDH1A1LMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116210474-A Plant cultivation method capable of reducing plant injury under ozone stress 中国科学院生态环境研究中心 2023-06-06 CN claimed
US-5001141-A N-(2-(2-oxo-1-imidazolidinyl)ethyl)-3-phenyl-urea and analogs as agents for induction of antioxidant enzymes E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-03-19 US claimed
CN-116210474-A Plant cultivation method capable of reducing plant injury under ozone stress 中国科学院生态环境研究中心 2023-06-06 CN disclosed
WO-1991018508-A1 COMPOSITION AGAINST OZONE DAMAGES TO CULTIVATIONS AND METHOD FOR ITS APPLICATION SOSTRA S.R.L. (IT) 1991-12-12 WO disclosed
US-5001141-A N-(2-(2-oxo-1-imidazolidinyl)ethyl)-3-phenyl-urea and analogs as agents for induction of antioxidant enzymes E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-03-19 US disclosed
US-5001141-A N-(2-(2-oxo-1-imidazolidinyl)ethyl)-3-phenyl-urea and analogs as agents for induction of antioxidant enzymes E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-03-19 US disclosed
US-5001141-A N-(2-(2-oxo-1-imidazolidinyl)ethyl)-3-phenyl-urea and analogs as agents for induction of antioxidant enzymes E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-03-19 US disclosed
WO-1990002804-A1 STRESS-TOLERANT PLANTS PLANT GENETIC SYSTEMS N.V. (BE) 1990-03-22 WO disclosed
EP-0359617-A2 Stress-tolerant plants PLANT GENETIC SYSTEMS, N.V. (BE) 1990-03-21 EP disclosed
US-4032638-A Heterocyclic ureas E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-06-28 US disclosed
US-3973946-A Substituted-3-phenyl ureas E. I. DUPONT DE NEMOURS & COMPANY (US) 1976-08-10 US disclosed