Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CCR3 | P51677 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GOT1 | P17174 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | IDH1 | O75874 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | UBE2M | P61081 | 1/20 | 0.47 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753886 | 0.82 | TSHR (0.66) | KDM4EKMT2AMEN1MAPTRAB9A | |
| SCHEMBL30041940 | 0.80 | EPHX2 (0.67) | CCR3KMT2AMEN1MAPTHTT | |
| SCHEMBL9765205 | 0.79 | KDM4E (0.47) | KDM4EKMT2ARAB9ALMNAALDH1A1 | |
| SCHEMBL9765206 | 0.79 | KDM4E (0.47) | KDM4EKMT2AMAPTRAB9ALMNA | |
| SCHEMBL9765181 | 0.78 | KDM4E (0.72) | KDM4EKMT2AMAPTRAB9ALMNA | |
| SCHEMBL30042757 | 0.77 | CCR3 (0.64) | CCR3KMT2AMEN1LMNAEPHX2 | |
| SCHEMBL14685427 | 0.76 | MAPT (0.66) | KDM4EKMT2AMEN1MAPTHTT | |
| SCHEMBL11710148 | 0.76 | CNR1 (0.62) | KDM4EKMT2AMAPTRAB9ALMNA | |
| SCHEMBL11192668 | 0.75 | MAPT (0.49) | KDM4ECCR3KMT2AMEN1MAPT | |
| SCHEMBL13737287 | 0.75 | MAPT (0.64) | KDM4EKMT2AMEN1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001141-A | N-(2-(2-oxo-1-imidazolidinyl)ethyl)-3-phenyl-urea and analogs as agents for induction of antioxidant enzymes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-03-19 | — | — | US | claimed |
| US-5001141-A | N-(2-(2-oxo-1-imidazolidinyl)ethyl)-3-phenyl-urea and analogs as agents for induction of antioxidant enzymes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-03-19 | — | — | US | disclosed |