Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | EGFR | P00533 | 1/20 | 0.56 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 3/20 | 0.55 |
| ▸ | MMP9 | P14780 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HTR7 | P34969 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | MMP14 | P50281 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9765301 | 1.00 | ALDH1A1 (0.67) | ALDH1A1POLBEGFRERBB2MMP2 | |
| SCHEMBL27284050 | 0.86 | ALDH1A1 (0.71) | ALDH1A1POLBMMP2MMP9CYP1A2 | |
| SCHEMBL9765250 | 0.86 | ALDH1A1 (0.57) | ALDH1A1POLBMMP2MMP9SMN1; SMN2 | |
| SCHEMBL9765267 | 0.83 | ADAMTS4 (0.55) | ALDH1A1POLBMMP2MMP9SMN1; SMN2 | |
| SCHEMBL9765251 | 0.83 | TBXA2R (0.60) | ALDH1A1POLBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9765276 | 0.83 | TBXA2R (0.60) | ALDH1A1POLBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9765248 | 0.83 | TBXA2R (0.60) | ALDH1A1POLBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9765320 | 0.82 | ALDH1A1 (0.57) | ALDH1A1POLBMMP2MMP9CYP1A2 | |
| SCHEMBL9707094 | 0.82 | ALDH1A1 (0.57) | ALDH1A1POLBMMP2MMP9CYP1A2 | |
| SCHEMBL9707087 | 0.82 | ALDH1A1 (0.57) | ALDH1A1POLBMMP2MMP9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255728-B1 | PHENOXYACETIC ACID COMPOUNDS, THEIR PREPARATION, PHARMACEUTICAL COMPOSITION AND USE | TANABE SEIYAKU CO., LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |
| US-4866196-A | ANTICOAGULANTS | TANABE SEIYAKU CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| EP-0255728-A2 | Phenoxyacetic acid compounds, their preparation, pharmaceutical composition and use | TANABE SEIYAKU CO., LTD. (JP) | 1988-02-10 | — | — | EP | disclosed |