Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MMP9 | P14780 | 4/20 | 0.54 |
| ▸ | MMP2 | P08253 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 2/20 | 0.50 |
| ▸ | MMP13 | P45452 | 2/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | MMP7 | P09237 | 1/20 | 0.50 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9765251 | 0.90 | TBXA2R (0.60) | ADAMTS4ALDH1A1POLBSMN1; SMN2NPSR1 | |
| SCHEMBL9765276 | 0.90 | TBXA2R (0.60) | ADAMTS4ALDH1A1POLBSMN1; SMN2NPSR1 | |
| SCHEMBL9765248 | 0.90 | TBXA2R (0.60) | ADAMTS4ALDH1A1POLBSMN1; SMN2NPSR1 | |
| SCHEMBL9510498 | 0.89 | ADRB2 (0.52) | ADAMTS4ALDH1A1POLBMMP9MMP2 | |
| SCHEMBL9765270 | 0.86 | KMT2A (0.54) | ADAMTS4ALDH1A1POLBMMP9MMP2 | |
| SCHEMBL7294664 | 0.85 | ITGB3 (0.51) | ADAMTS4ALDH1A1POLBSMN1; SMN2NPSR1 | |
| Hydrochloric Acid SCHEMBL9261313 | 0.85 | ITGB3 (0.52) | ADAMTS4ALDH1A1POLBSMN1; SMN2NPSR1 | |
| SCHEMBL9765250 | 0.84 | ALDH1A1 (0.57) | ADAMTS4ALDH1A1POLBMMP9MMP2 | |
| SCHEMBL9765301 | 0.83 | ALDH1A1 (0.67) | ALDH1A1POLBMMP9MMP2SMN1; SMN2 | |
| SCHEMBL9765257 | 0.83 | ALDH1A1 (0.67) | ALDH1A1POLBMMP9MMP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255728-B1 | PHENOXYACETIC ACID COMPOUNDS, THEIR PREPARATION, PHARMACEUTICAL COMPOSITION AND USE | TANABE SEIYAKU CO., LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |
| US-4866196-A | ANTICOAGULANTS | TANABE SEIYAKU CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| EP-0255728-A2 | Phenoxyacetic acid compounds, their preparation, pharmaceutical composition and use | TANABE SEIYAKU CO., LTD. (JP) | 1988-02-10 | — | — | EP | disclosed |