SCHEMBL976528

SCHEMBL976528

C=Cc1ccc(-c2cccs2)s1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 4/20 0.65
ALDH1A1 P00352 7/20 0.51
KDM4E B2RXH2 6/20 0.51
L3MBTL1 Q9Y468 4/20 0.51
GAA P10253 3/20 0.51
HSD17B10 Q99714 3/20 0.51
MAPT P10636 3/20 0.51
MEN1 O00255 3/20 0.51
HPGD P15428 3/20 0.51
KMT2A Q03164 3/20 0.51
GLA P06280 2/20 0.51
POLB P06746 2/20 0.51
CASP1 P29466 2/20 0.51
CASP7 P55210 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
USP2 O75604 1/20 0.51
THRB P10828 1/20 0.51
ALOX15 P16050 1/20 0.51
TSHR P16473 1/20 0.51
ALOX12 P18054 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL975461 0.98 DPP4 (0.68) DPP4ALDH1A1KDM4EL3MBTL1GAA
SCHEMBL22733860 0.87 DPP4 (0.50) DPP4ALDH1A1KDM4EL3MBTL1GAA
SCHEMBL30375911 0.83 DPP4 (0.69) DPP4ALDH1A1KDM4EL3MBTL1GAA
SCHEMBL19721713 0.83 DPP4 (0.69) DPP4ALDH1A1KDM4EL3MBTL1GAA
SCHEMBL29493701 0.82 DPP4 (0.39) DPP4ALDH1A1KDM4EL3MBTL1GAA
SCHEMBL6852250 0.81 DPP4 (0.61) DPP4ALDH1A1KDM4EL3MBTL1GAA
SCHEMBL14552134 0.80 DPP4 (0.42) DPP4ALDH1A1KDM4EL3MBTL1GAA
SCHEMBL223830 0.80 DPP4 (0.96) DPP4ALDH1A1KDM4EL3MBTL1GAA
SCHEMBL498654 0.78 DPP4 (1.00) DPP4ALDH1A1KDM4EL3MBTL1GAA
SCHEMBL16081599 0.78 DPP4 (1.00) DPP4ALDH1A1KDM4EL3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113707808-A Intrinsic stretchable organic parallel heterojunction phototransistor and preparation method thereof 中国科学院化学研究所 2021-11-26 CN claimed
US-20100221646-A1 HOLOGRAPHIC RECORDING MEDIUM KABUSHIKI KAISHA TOSHIBA (JP) 2010-09-02 US claimed
CN-113707808-A Intrinsic stretchable organic parallel heterojunction phototransistor and preparation method thereof 中国科学院化学研究所 2021-11-26 CN disclosed
US-8475937-B2 Silicone composition and organic light-emitting diode DOW CORNING CORPORATION (US) 2013-07-02 US disclosed
US-20120264649-A1 AGENTS FOR ENHANCED CHARGE TRANSPORT ACROSS MICROBIAL MEMBRANES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2012-10-18 US disclosed
US-20120264649-A1 AGENTS FOR ENHANCED CHARGE TRANSPORT ACROSS MICROBIAL MEMBRANES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2012-10-18 US disclosed
EP-2262861-B1 SILICONE COMPOSITION AND ORGANIC LIGHT-EMITTING DIODE DOW CORNING (US) 2012-09-19 EP disclosed
US-20110017986-A1 Silicone Composition and Organic Light-Emitting Diode DOW CORNING CORPORATION 2011-01-27 US disclosed
EP-2262861-A1 SILICONE COMPOSITION AND ORGANIC LIGHT-EMITTING DIODE Dow Corning Corporation (US) 2010-12-22 EP disclosed
US-7795529-B2 Organic dye, photoelectric conversion material, semiconductor electrode and photoelectric conversion device MITSUBISHI PAPER MILLS LTD. (JP) 2010-09-14 US disclosed
US-7795529-B2 Organic dye, photoelectric conversion material, semiconductor electrode and photoelectric conversion device MITSUBISHI PAPER MILLS LTD. (JP) 2010-09-14 US disclosed
US-7615640-B2 Organic dye, photoelectric conversion material, semiconductor electrode and photoelectric conversion device Mitsubishi PaperMillsLtd. (JP) 2009-11-10 US disclosed
WO-2009120434-A1 SILICONE COMPOSITION AND ORGANIC LIGHT-EMITTING DIODE DOW CORNING CORPORATION (US) 2009-10-01 WO disclosed
US-20080149175-A1 Organic dye, photoelectric conversion material, semiconductor electrode and photoelectric conversion device HORIUCHI TAMOTSU 2008-06-26 US disclosed
US-20080149175-A1 Organic dye, photoelectric conversion material, semiconductor electrode and photoelectric conversion device HORIUCHI TAMOTSU 2008-06-26 US disclosed
US-20080087327-A1 Organic dye, photoelectric conversion material, semiconductor electrode and photoelectric conversion device HORIUCHI TAMOTSU 2008-04-17 US disclosed
US-20080087327-A1 Organic dye, photoelectric conversion material, semiconductor electrode and photoelectric conversion device HORIUCHI TAMOTSU 2008-04-17 US disclosed
US-20070078120-A1 Novel piperidine derivative DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2007-04-05 US disclosed
WO-2006076247-A2 PHOSPHORESCENT FLUORENE, ANTHRACENE AND/OR THIOPHENE SUBSTITUTED METALLO- PORPHYRINS AND RELATED COMPOUNDS GENERAL ELECTRIC COMPANY (US) 2006-07-20 WO disclosed
US-20060152149-A1 Porphyrin compositions GENERAL ELECTRIC COMPANY (US) 2006-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070078120-A1 Novel piperidine derivative LDLR, PRMT5, MSR1 DPP4 999/4885ALDH1A1 2990/4885KDM4E 728/4885
US-20060152149-A1 Porphyrin compositions ACP1, MMS19, MVD DPP4 4570/4885ALDH1A1 1882/4885KDM4E 2546/4885
US-20080149175-A1 Organic dye, photoelectric conversion material, semiconductor electrode and photoelectric conversion device FTO, PPOX, CDH1 DPP4 2360/4885ALDH1A1 1190/4885KDM4E 536/4885
US-20080087327-A1 Organic dye, photoelectric conversion material, semiconductor electrode and photoelectric conversion device FTO, PPOX, CDH1 DPP4 2360/4885ALDH1A1 1190/4885KDM4E 536/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.